What are the discharge instructions for an 11-month-old patient with otitis media (middle ear infection) being treated with amoxicillin (amoxicillin)?

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Last updated: January 11, 2026View editorial policy

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Discharge Instructions for 11-Month-Old with Otitis Media on Amoxicillin

Complete the full 10-day course of amoxicillin even if your child feels better before finishing the medication, as stopping early increases the risk of treatment failure and antibiotic resistance. 1, 2

Medication Administration

  • Give amoxicillin exactly as prescribed (80-90 mg/kg/day divided into 2-3 equal doses) at evenly spaced intervals throughout the day 2, 3
  • Shake the suspension bottle well before each dose to ensure proper mixing 4
  • Use the calibrated oral syringe provided with the medication—never use household spoons, as they are inaccurate 4
  • Rinse the oral syringe after each use to prevent medication buildup 4
  • Refrigeration is preferred but not required for the suspension; keep the bottle tightly closed 4
  • Discard any unused suspension after 14 days from when it was mixed 4

Pain Management

  • Give pain medication (acetaminophen or ibuprofen) regularly during the first 24-48 hours, even if your child seems comfortable, as pain control is essential regardless of antibiotic use 1, 2
  • Continue pain medication as needed for ear discomfort 1

When to Seek Immediate Medical Attention

Return to the clinic or emergency department immediately if any of these occur:

  • Worsening symptoms or no improvement within 48-72 hours of starting antibiotics (persistent fever, increased irritability, worsening ear pain) 1, 3
  • New or worsening fever ≥39°C (102.2°F) after starting treatment 2, 5
  • Skin rash, hives, or facial swelling, which may indicate an allergic reaction 4
  • Severe diarrhea (≥3 watery stools in one day or bloody stools), which can occur even weeks after finishing antibiotics 1, 4
  • Drainage from the ear (otorrhea) that develops or worsens 5
  • Extreme irritability or lethargy beyond what you've already observed 2

Expected Course and Follow-Up

  • Symptoms should begin improving within 48-72 hours of starting antibiotics, though complete resolution may take the full 10 days 1
  • Fluid behind the eardrum (middle ear effusion) is normal after treatment and can persist for 2-8 weeks without indicating treatment failure 1
  • Routine follow-up visits are not necessary for uncomplicated cases if your child improves as expected 5
  • Consider a follow-up examination if your child has recurrent ear infections or if you have concerns about hearing 5

Important Warnings

  • Never save leftover antibiotics for future illnesses or share them with others 4
  • Antibiotics only treat bacterial infections, not viral illnesses like colds 4
  • Watch for signs of yeast diaper rash (candidal infection), which can occur as a side effect of antibiotics 6
  • Common side effects include diarrhea (occurs in 14-34% of children), which usually resolves after completing treatment 6

Prevention of Future Infections

  • Ensure your child is up to date on pneumococcal (PCV-13) and annual influenza vaccines, which help prevent recurrent ear infections 2
  • Avoid exposing your child to secondhand smoke 2

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Treatment for Acute Otitis Media in Infants

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Guideline

Acute Otitis Media Treatment Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Guideline

Acute Otitis Media Treatment Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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