What is the management for tympanic membrane retraction grades 1 to 4 in Tuberculosis of the Ossicles (TOS)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: April 12, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Research

Management of tympanic membrane retractions (TOS grades 1-4) should be tailored to the severity of the retraction and underlying causes, with a focus on watchful waiting for mild to moderate cases and surgical intervention for severe cases with complications. For mild retractions (TOS 1-2), start with medical management including nasal steroids like fluticasone (2 sprays per nostril daily) or mometasone (1-2 sprays per nostril daily) for at least 3-6 months to improve Eustachian tube function, as suggested by the general approach to managing Eustachian tube dysfunction 1. Combine this with regular Valsalva maneuvers (3-5 times daily) and treatment of any underlying allergies or sinusitis. For moderate retractions (TOS 3), consider myringotomy with ventilation tube insertion if medical management fails after 3 months, although the evidence for this approach is not strong 2. For severe retractions (TOS 4) with ossicular chain erosion or cholesteatoma formation, surgical intervention is typically necessary, ranging from tympanoplasty to more extensive procedures depending on the extent of damage. Regular follow-up with otoscopic examination every 3-6 months is essential for all grades to monitor progression, as emphasized by the study on the natural course of tympanic membrane retractions 3. The goal of treatment is to equalize middle ear pressure and prevent progression to more severe retraction, adhesive otitis media, or cholesteatoma. Eustachian tube dysfunction is the primary underlying cause, leading to negative middle ear pressure that pulls the tympanic membrane inward, so addressing this dysfunction is crucial for successful management. Some studies suggest that watchful waiting may be a viable option for some patients, with low rates of complications and progression to more severe disease 3. However, the decision to pursue watchful waiting or surgical intervention should be made on a case-by-case basis, taking into account the individual patient's symptoms, underlying health status, and preferences. Ultimately, the management of tympanic membrane retractions requires a personalized approach, with careful consideration of the potential benefits and risks of different treatment strategies. Key considerations include:

  • The severity of the retraction and underlying causes
  • The presence of complications such as ossicular chain erosion or cholesteatoma formation
  • The patient's overall health status and preferences
  • The potential benefits and risks of different treatment strategies, including watchful waiting and surgical intervention. Given the most recent and highest quality study available 3, a watchful waiting policy may be considered for patients with mild to moderate tympanic membrane retractions, while surgical intervention is typically necessary for severe cases with complications.

References

Research

Management of tympanic membrane retractions: a systematic review.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2022

Research

Long-term middle-ear ventilation with subannular tubes.

The Journal of laryngology and otology, 2010

Research

The Natural Course of Tympanic Membrane Retractions in the Posterosuperior Quadrant of Pars Tensa: A Watchful Waiting Policy.

Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2021

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.