From the FDA Drug Label
In uncomplicated urinary tract infections, skin and skin-structure infections, disseminated gonococcal infections, and uncomplicated pneumonia, a 750 mg dose every 8 hours is recommended. The recommended dose and frequency of Ceftin (cefuroxime) for a urinary tract infection (UTI) is 750 mg every 8 hours.
- The duration of treatment is usually 5 to 10 days.
- In cases of impaired renal function, the dosage should be adjusted according to the degree of renal impairment and the susceptibility of the causative organism 1.
From the Research
Ceftin (cefuroxime) is typically prescribed for urinary tract infections (UTIs) at a dose of 250-500 mg taken orally twice daily, usually for 7-10 days, with the most recent evidence suggesting that twice-daily dosing is as effective as four-times-daily dosing for uncomplicated UTIs 2. For uncomplicated UTIs, 250 mg twice daily is often sufficient, while more severe or complicated infections may require the higher 500 mg dose. The medication should be taken with food to enhance absorption and reduce stomach upset. It's essential to complete the entire prescribed course even if symptoms improve before finishing the medication to ensure complete eradication of the infection. Ceftin works by inhibiting bacterial cell wall synthesis, effectively killing the bacteria causing the UTI. Common side effects may include diarrhea, nausea, and headache. Patients should drink plenty of water while taking this medication to help flush the urinary system. If symptoms worsen or don't improve after a few days of treatment, patients should contact their healthcare provider as a different antibiotic may be needed based on bacterial sensitivity testing. Some key points to consider when prescribing Ceftin for UTIs include:
- The importance of completing the full treatment course to prevent recurrence and resistance
- The need to monitor for side effects and adjust the treatment plan as necessary
- The potential for interactions with other medications, such as antacids and blood thinners
- The importance of staying hydrated to help the medication work effectively
- The potential for Ceftin to be less effective against certain types of bacteria, such as ESBL-producing Enterobacteriaceae 3. Overall, Ceftin can be an effective treatment option for UTIs when used appropriately and with careful consideration of the potential benefits and risks.