What is the diagnosis for a unilateral headache that worsens with standing and improves with lying down?

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Differential Diagnosis for Headache

  • Single most likely diagnosis
    • Postural headache (e.g., postural orthostatic tachycardia syndrome or orthostatic headache): The headache is worse with standing and improves with lying down, which suggests a postural component.
  • Other Likely diagnoses
    • Tension headache: The sharp pain on one side of the forehead could be consistent with a tension headache, although the postural component is not typical.
    • Migraine: Although the headache is not severe (3/10) and lacks associated symptoms, some migraines can present with mild pain and without aura or other features.
    • Sinus headache: The location of the pain on the right side of the forehead could suggest a sinus headache, but the lack of other symptoms such as nasal congestion or facial pressure makes this less likely.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Subarachnoid hemorrhage: Although the headache is not severe and lacks sudden onset, any new headache with a postural component warrants consideration of a subarachnoid hemorrhage.
    • Intracranial hypotension: This condition can cause a postural headache that worsens with standing and improves with lying down, and it is essential to consider it to avoid missing a potentially treatable cause.
    • Cerebral venous sinus thrombosis: This rare condition can cause headache, and although it is unlikely, it is crucial to consider it due to its potential severity.
  • Rare diagnoses
    • Temporomandibular joint disorder: This condition can cause referred pain to the forehead, but it would typically be associated with jaw pain or clicking.
    • Occipital neuralgia: This condition involves inflammation of the occipital nerve and can cause sharp pain on one side of the head, but it is relatively rare.
    • Hypnic headache: This rare condition causes headache that occurs only when lying down and wakes the patient from sleep, which does not match the patient's symptoms.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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