From the Guidelines
DX-9065A is a novel, synthetic, selective, and orally active inhibitor of factor Xa that stops with the letter "a" in its name. This medication is highlighted in a study published in the journal Drug Metab Dispos in 2009, as referenced by 1. The study discusses DX-9065A's in vitro and in vivo properties as a factor Xa inhibitor, which is crucial in antithrombotic therapy. Key points about DX-9065A include:
- It is a selective inhibitor of factor Xa, which plays a significant role in the coagulation cascade.
- The drug has been studied for its potential in preventing thrombosis, as mentioned in the context of the American College of Chest Physicians evidence-based clinical practice guidelines 1.
- As a synthetic and orally active compound, DX-9065A offers a convenient route of administration for patients requiring antithrombotic therapy.
- Its mechanism of action, inhibiting factor Xa, is a targeted approach to preventing thrombus formation, which can lead to conditions such as deep vein thrombosis or pulmonary embolism.
- The development and study of DX-9065A, as noted in the 2009 publication 1, contribute to the evolving landscape of antithrombotic drugs, providing healthcare providers with more options for managing and preventing thrombotic events.
From the Research
Drug Information
- The provided studies do not directly answer the question about a drug that stops with "x" in it, but they do discuss various triptan drugs used for migraine treatment, such as rizatriptan, zolmitriptan, naratriptan, eletriptan, almotriptan, and frovatriptan 2, 3, 4, 5, 6.
- Among these, the drugs that end with the letter combination including "x" are not explicitly mentioned in the context of stopping with "x", but rather as part of their names or classifications.
- Rizatriptan is mentioned in several studies as an effective drug for the acute treatment of moderate or severe migraine, with a faster onset of action compared to some other triptans 2, 3, 4, 5, 6.
Triptan Drugs
- The studies compare the efficacy, safety, and tolerability of different triptan drugs, including sumatriptan, zolmitriptan, rizatriptan, naratriptan, almotriptan, eletriptan, and frovatriptan 4, 5, 6.
- Rizatriptan, in particular, is noted for its rapid onset of action and effectiveness in providing pain relief and a pain-free state, as well as relieving associated symptoms of migraine 2, 3.
- The choice of triptan drug may depend on individual patient needs and preferences, as well as the specific characteristics of each drug, such as onset of action, efficacy, and adverse event profile 6.