What is the duration of action of Journavax (vaccine) in providing immunity?

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Journavax Duration of Action

I cannot provide specific information about "Journavax" as this vaccine name does not appear in any of the provided evidence or established medical literature for Japanese Encephalitis vaccines.

Clarification Needed

The evidence provided discusses two Japanese Encephalitis vaccines:

  • JE-VC (Vero cell-derived vaccine, marketed as Ixiaro)
  • JE-MB (Mouse brain-derived vaccine, no longer widely available)

If you are asking about a Japanese Encephalitis vaccine, please clarify which specific product you are referring to. The duration of protection varies significantly between vaccine types:

For JE-VC (Ixiaro) - Most Commonly Used Currently:

After completing the 2-dose primary series, protective antibody levels persist in approximately 90% of adults for at least 2-3 years, with evidence suggesting protection may extend beyond this period. 1

  • Primary series protection: 90% of children maintained seroprotection at 11,23, and 35 months after the 2-dose primary series 1
  • After booster dose: Mathematical modeling estimates protection lasts an average of 14 years (range: 2-25 years) following a booster dose 1
  • At 6 years post-booster: 96% of adults still maintained protective antibody titers 1

For JE-MB (Older Vaccine):

  • Primary series protection: Neutralizing antibodies persist for at least 2 years after completing the 3-dose primary series 1
  • Booster recommendations: A booster dose may be administered 2 years after the primary series 1

Please confirm the exact vaccine name or brand to receive accurate duration of action information specific to that product.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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