With a normal FSH level and low sperm count, is testicular atrophy likely and is azoospermia unlikely in a male of reproductive age?

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Last updated: January 12, 2026View editorial policy

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Assessment of Your FSH and Sperm Count Results

With an FSH of 9.9 IU/L (within normal laboratory range) and sperm count of 56 million/mL (well above the normal threshold of >16 million/mL), testicular atrophy is unlikely and azoospermia is extremely unlikely. 1

Understanding Your Results

Your laboratory values indicate preserved testicular function:

  • Your sperm concentration of 56 million/mL exceeds the normal threshold of >16 million/mL defined by the American Urological Association, indicating adequate sperm production 1
  • Your FSH level of 9.9 IU/L falls within the normal reference range (1-12.4 IU/L) and does not suggest significant testicular dysfunction 1
  • FSH levels >7.6 IU/L are associated with non-obstructive azoospermia and testicular dysfunction, but this applies to men with absent or severely reduced sperm counts, not your situation with normal sperm concentration 2

Why Testicular Atrophy Is Unlikely

The combination of your parameters argues against testicular atrophy:

  • Men with testicular atrophy typically present with both elevated FSH (often >12 IU/L) and severely reduced or absent sperm production 3, 4
  • Your normal sperm count of 56 million/mL indicates functioning seminiferous tubules, which would not be present with significant testicular atrophy 1
  • FSH levels correlate negatively with spermatogenesis - higher FSH reflects the pituitary's attempt to compensate for reduced testicular function, but your FSH remains in the normal range 5

Why Azoospermia Is Extremely Unlikely

Azoospermia (complete absence of sperm) is not a concern in your case:

  • You already have documented sperm production at 56 million/mL, which by definition excludes azoospermia 1
  • Even men with FSH levels significantly higher than yours (>20 mIU/mL) and testicular atrophy can have sperm recovery rates of 24-30% 6, 4
  • Azoospermia typically occurs with FSH levels well above 12 IU/L in the context of primary testicular failure, not with your current parameters 3

Important Context About FSH Interpretation

While your FSH is in the upper portion of the normal range, this requires nuanced interpretation:

  • Some research suggests FSH levels >4.5 IU/L may be associated with abnormal sperm morphology or concentration in infertile populations, but this applies to men with documented fertility problems, not necessarily to all men with FSH in this range 7
  • FSH shows natural variation among healthy men, with some individuals maintaining levels in the 9-12 IU/L range while maintaining normal fertility 1
  • Your documented normal sperm count overrides concerns about borderline FSH elevation - the actual sperm production is what matters most 1

Critical Pitfalls to Avoid

Never start testosterone supplementation if you have any interest in current or future fertility - exogenous testosterone will suppress spermatogenesis through negative feedback on the hypothalamus and pituitary, potentially causing azoospermia that can take months to years to recover 8, 1, 2

When to Seek Further Evaluation

Consider additional workup only if:

  • You are actively trying to conceive and pregnancy has not occurred after 12 months of regular unprotected intercourse 8
  • Complete semen analysis (including motility and morphology) reveals abnormalities beyond just concentration 1
  • You develop symptoms of testosterone deficiency (decreased libido, erectile dysfunction, fatigue) - in which case measure testosterone and LH alongside repeat FSH 8, 1

References

Guideline

FSH Levels and Male Fertility

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Management of Men with Borderline FSH Levels

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Guideline

Management of Elevated FSH with Low Sperm Count or Azoospermia

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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