What is the diagnosis for a patient with a history of asthma, showing no acute intrathoracic findings on Computed Tomography Angiography (CTA), with unremarkable Complete Blood Count (CBC) and Comprehensive Metabolic Panel (CMP), normal troponin and d-dimer levels, and bilateral lung wheezing?

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Differential Diagnosis

  • Single most likely diagnosis
    • Asthma exacerbation: The patient has a history of asthma, and the presence of wheezing over bilateral lungs is a classic symptom of an asthma exacerbation. The unremarkable CBC, CMP, and low troponin and d-dimer levels also support this diagnosis.
  • Other Likely diagnoses
    • Chronic obstructive pulmonary disease (COPD) exacerbation: Although the patient has a history of asthma, COPD could also be a consideration, especially if the patient has a history of smoking or other risk factors.
    • Allergic reaction: The patient's upper airway disease and wheezing could be related to an allergic reaction, which could be causing bronchospasm and wheezing.
    • Viral upper respiratory infection: A viral infection could be causing the patient's upper airway disease and wheezing, especially if the patient has a history of recent illness.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Pulmonary embolism (PE): Although the d-dimer is low, a PE could still be present, especially if the patient has a history of risk factors such as recent travel or immobility.
    • Cardiac tamponade: The patient's wheezing and shortness of breath could be related to a cardiac tamponade, which would require immediate attention.
    • Pneumothorax: A pneumothorax could be causing the patient's wheezing and shortness of breath, and would require immediate attention.
  • Rare diagnoses
    • Cystic fibrosis: Although rare, cystic fibrosis could be a consideration in a patient with chronic respiratory symptoms and wheezing.
    • Bronchiolitis obliterans: This rare condition could be causing the patient's wheezing and shortness of breath, especially if the patient has a history of lung injury or infection.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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