What are the health risks associated with electronic cigarette (e-cigarette) use?

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Last updated: April 13, 2025View editorial policy

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From the Guidelines

Vaping poses significant health risks, including lung damage, cardiovascular problems, and nicotine addiction, and individuals with diabetes should be advised to avoid vaping and using e-cigarettes. The most recent and highest quality study, published in 2025 1, highlights the importance of avoiding vaping and e-cigarettes due to their potential health risks, which affect the cardiovascular and respiratory systems.

Key Risks Associated with Vaping

  • Lung damage and cardiovascular problems
  • Nicotine addiction
  • Serious lung injuries, including EVALI (e-cigarette or vaping product use-associated lung injury)
  • Explosion and burn risks from high-powered batteries
  • Gateway to traditional cigarette smoking, especially among young people

Recommendations for Individuals with Diabetes

  • Avoid vaping and using e-cigarettes
  • Include smoking cessation counseling and other forms of treatment as a routine component of diabetes care
  • Address smoking cessation as part of diabetes education programs for those in need

The evidence from the 2025 study 1 and other recent studies 1 emphasizes the importance of avoiding vaping and e-cigarettes due to their potential health risks. While vaping might help some smokers transition away from combustible cigarettes, it is not approved as a smoking cessation tool, and non-smokers should avoid starting vaping due to these substantial health risks.

Importance of Smoking Cessation Counseling

  • Brief counseling and pharmacologic therapy can be effective in reducing tobacco use
  • Assessment of level of nicotine dependence is essential to prevent smoking or encourage cessation
  • Diabetes education programs can offer potential to systematically reach and engage individuals with diabetes in smoking cessation efforts

Overall, the risks associated with vaping and e-cigarettes outweigh any potential benefits, and individuals with diabetes should be advised to avoid these products and focus on evidence-based smoking cessation methods.

From the Research

Risks of Vaping

  • The use of electronic cigarettes (e-cigarettes) may pose health risks, including cardiovascular and respiratory diseases 2.
  • Acute lung injury may also be associated with the use of e-cigarettes, but the underlying cause remains unknown 2.
  • The components and constituents of e-cigarettes, such as propylene glycol and glycerin, may adversely impact health by generating pulmonary irritants and carcinogenic carbonyl compounds 3.
  • Metals contained in heating coils and cartridge casings may leach metals such as aluminum, chromium, iron, lead, manganese, nickel, and tin, which can be harmful to health 3.
  • Flavoring agents, such as diacetyl, have known pulmonary toxicity with inhalational exposures leading to bronchiolitis obliterans 3.

Health Consequences of Vaping

  • The outbreak of e-cigarette, or vaping, product use-associated lung injury (EVALI) in 2019 highlighted the need for regulation of e-cigarette devices and e-liquids 3.
  • Vitamin E acetate (VEA) used as a diluent in tetrahydrocannabinol vape cartridges is implicated in EVALI, and its use can lead to the accumulation of VEA in pulmonary tissue 3.
  • Patients with EVALI present with a constellation of respiratory, gastrointestinal, and constitutional symptoms, and radiographically have bilateral ground glass opacifications 3.
  • As of February 18,2020, the Centers for Disease Control has identified 2807 hospitalized patients diagnosed with either "confirmed" or "probable" EVALI in the US 3.

Comparison with Smoking Cessation Methods

  • Nicotine replacement therapy (NRT), bupropion, and varenicline are commonly used methods for smoking cessation, but their effectiveness may vary 4, 5, 6.
  • Varenicline has been shown to be as effective as or more effective than bupropion for smoking cessation 4, 6.
  • Combination NRT and higher-dose NRT did not demonstrate consistent effects over other interventions, and their benefits were not retained in the long term 6.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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