What are the best management options for an elderly female patient with a history of heart failure with preserved ejection fraction (HFpEF), complete heart block/atrial fibrillation with a pacemaker, coronary artery disease (CAD), chronic kidney disease stage 3a (CKD 3a), uremia, hypertension (HTN), hyperlipidemia, pulmonary hypertension (Pulm HTN), bilateral lower extremity edema due to severe peripheral arterial disease (PAD), gastroesophageal reflux disease (GERD) with hiatal hernia, and failure to thrive, who is a Do Not Resuscitate (DNR) and has been refusing to eat and has hypothermia after removal of her nasogastric (NG) tube?

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Management of an Elderly DNR Patient with HFpEF, Multiple Comorbidities, Refusing Nutrition, and Hypothermia

This patient requires a transition to palliative care and hospice services, as she meets criteria for end-stage heart failure (Stage D) with multiple life-limiting comorbidities, is refusing life-sustaining interventions, and demonstrates signs of active dying with hypothermia. 1

Recognition of End-Stage Disease

This patient has Stage D heart failure—characterized by marked symptoms at rest despite optimal medical therapy, recurrent hospitalizations, and inability to perform activities of daily living. 1 Her refusal to eat, removal of the NG tube, and hypothermia (96.1°F) are clinical indicators of the dying phase. 1

Key indicators that further aggressive intervention is not beneficial:

  • Recurrent hospitalizations despite medical management 1
  • Multiple severe comorbidities (HFpEF, CKD 3a with uremia, severe PAD, complete heart block, CAD, pulmonary hypertension) 1
  • Failure to thrive with refusal of nutritional support 1
  • DNR status indicating patient preference against aggressive measures 1
  • Hypothermia suggesting impending death 1

Ethical Framework for Nutrition and Hydration

Artificial nutrition and hydration should be withheld in this dying patient, as it provides no benefit and may cause harm. 1

The ESPEN guidelines clearly state that nutritional therapy has no benefit in dying patients who are unable to eat normally. 1 A nasogastric tube causes discomfort and risks aspiration and coughing. 1 Most dying patients are not hungry or thirsty, and the normal hypotension, hypoxia, and hypercapnia that underlie natural dying may be prolonged when patients receive rehydration fluids. 1

When the patient is competent and refuses food or fluids, she may not be forced to receive them. 1 This patient has demonstrated her wishes by actively removing her NG tube. 1

Appropriate Management Strategy

Immediate Comfort-Focused Care

Shift all management to symptom control and comfort measures only:

  • Discontinue monitoring of vital signs beyond what is necessary for comfort assessment 1
  • Stop daily weights and fluid balance charts as volume management is no longer a therapeutic goal 2
  • Discontinue routine laboratory monitoring (renal function, electrolytes) unless needed to guide symptom management 1, 2

Symptom Management

Address specific symptoms with palliative interventions:

  • For dyspnea: Administer low-dose opiates (morphine) to relieve breathlessness 1
  • For pain or discomfort: Use appropriate low-dose opiates 1
  • For agitation or distress: Consider low-dose sedatives for palliative sedation 1
  • For dry mouth: Provide mouth care with moistened swabs, but do not force oral intake 1
  • For skin breakdown: Continue comfort measures for decubitus ulcers and incontinence 1

Diuretic Management

Discontinue or dramatically reduce diuretics as aggressive volume management is not beneficial in the dying phase and may prolong suffering. 1 The bilateral lower extremity edema from severe PAD does not require treatment when the goal is comfort. 1

Medication Review

Discontinue medications that do not contribute to comfort:

  • Stop guideline-directed medical therapy for heart failure (ACE inhibitors, beta-blockers, aldosterone antagonists) as survival benefit is no longer relevant 1
  • Discontinue medications for chronic disease management (statins, antihypertensives beyond symptom control) 1
  • Continue only medications that provide symptom relief 1

Management of Hypothermia

Do not attempt to rewarm the patient aggressively. 1 Hypothermia (temperature 96.1°F) in this context is a natural part of the dying process, reflecting decreased metabolic activity and impending death. 1 Provide warm blankets for comfort if the patient appears cold, but recognize this as a sign of approaching death rather than a problem requiring intervention. 1

Hospice Referral and Goals of Care

Immediate hospice referral is indicated for this Stage D heart failure patient with DNR status. 1, 3

ACC/AHA guidelines explicitly list hospice care as an appropriate option for Stage D heart failure patients who have marked symptoms at rest despite maximal medical therapy and are recurrently hospitalized. 1

Essential components of the hospice transition:

  • Document goals of care discussion with patient (if capable) and family regarding prognosis and comfort-focused care 1, 3
  • Provide psychosocial support to patient and family during this transition 1
  • Ensure 24-hour access to hospice team for symptom management 1
  • Educate family about the dying process, including what to expect with hypothermia, decreased responsiveness, and changes in breathing patterns 1

Common Pitfalls to Avoid

Do not reinitiate artificial nutrition or hydration. 1 The patient has clearly expressed her wishes by removing the NG tube, and forcing nutrition in a dying patient causes suffering without benefit. 1

Do not treat hypothermia as a medical emergency requiring aggressive intervention. 1 In the context of end-stage disease with refusal of nutrition, hypothermia is part of the natural dying process. 1

Do not continue aggressive diuresis or volume management. 1 While heart failure guidelines emphasize achieving euvolemia in patients being treated for survival, this patient is dying and such interventions may prolong suffering. 1

Do not delay hospice referral. 1, 3 Early involvement of palliative care improves quality of life and provides essential support to patients and families. 3

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Management of Heart Failure with Acute Kidney Injury

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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