From the FDA Drug Label
The FDA drug label does not answer the question.
From the Research
Definition and Properties of Terbinafine
- Terbinafine is an orally and topically active allylamine antifungal agent with a primarily fungicidal action in vitro 1, 2.
- It inhibits the biosynthesis of the principal sterol in fungi, ergosterol, at the level of squalene epoxidase, resulting in ergosterol-depleted fungal cell membranes and the toxic accumulation of intracellular squalene 3.
- Terbinafine has demonstrated excellent fungicidal activity against dermatophytes and variable activity against yeasts and non-dermatophyte molds in vitro 3, 1.
Forms and Uses of Terbinafine
- Terbinafine is available in oral and topical forms, including a 1% cream and a 250 mg/day oral tablet 1, 2.
- It is used to treat superficial fungal infections, including onychomycosis, tinea pedis, tinea corporis/cruris, and tinea capitis 3, 1, 4, 2.
- Terbinafine has also been used to treat non-dermatophyte infections, including azole-resistant candidiasis, invasive aspergillosis, disseminated fusariosis, and scedosporiosis 5.
Efficacy and Safety of Terbinafine
- Terbinafine has demonstrated high efficacy in treating dermatophyte infections, with mycological cure rates of > 80% in many studies 3, 1, 2.
- It is generally well tolerated, with a low potential for drug interactions and a relatively low incidence of adverse effects 3, 1, 2.
- Terbinafine has been shown to be effective and safe in children, with a high cure rate and a low incidence of adverse effects 4.
Terbinafine Liquid
- There is no specific information available on Terbinafine liquid in the provided studies.