What is the ICD-10 (International Classification of Diseases, 10th Revision) code for a routine mammogram screening in an asymptomatic female between 40 and 74 years old?

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ICD-10 Code for Routine Mammogram Screening

For routine screening mammography in asymptomatic women aged 40-74 years, use ICD-10 code Z12.31 (Encounter for screening mammogram for malignant neoplasm of breast).

Primary Screening Code

  • Z12.31 is the appropriate ICD-10 code for routine screening mammography in asymptomatic average-risk women 1.
  • This code specifically designates an encounter for screening purposes, distinguishing it from diagnostic mammography performed for symptomatic patients or follow-up of abnormalities 1.

Age-Specific Screening Recommendations

The screening code Z12.31 applies across the following age groups, though screening frequency varies:

Women Ages 40-44

  • Screening mammography is recommended with the code Z12.31, though guidelines vary on whether to begin at age 40 or 45 1, 2.
  • The American Cancer Society suggests women have the opportunity to begin annual screening between ages 40-44 1.

Women Ages 45-54

  • Annual screening mammography is strongly recommended, coded as Z12.31 1, 2.
  • The American Cancer Society recommends annual screening starting at age 45 1.

Women Ages 50-69

  • Biennial screening is recommended by most guidelines, though annual screening provides greater mortality reduction (40% vs 23%) 1, 2.
  • Use Z12.31 for these screening encounters 1.

Women Ages 70-74

  • Screening continues with Z12.31 if life expectancy exceeds 10 years 1, 2.
  • European guidelines suggest triennial screening over biennial in this age group 1.

Important Coding Distinctions

Do not confuse screening with diagnostic mammography:

  • Z12.31 is exclusively for asymptomatic screening in average-risk women 1.
  • Diagnostic mammography (for symptomatic patients or abnormality follow-up) requires different coding based on the specific indication 1.

Additional considerations:

  • Women with personal history of breast cancer, genetic mutations (BRCA1/BRCA2), or other high-risk factors may require different coding to reflect their elevated risk status 2.
  • The screening code Z12.31 should only be used in the context of organized screening programs with appropriate quality standards 1.

Clinical Context for Proper Code Usage

  • Screening mammography reduces breast cancer mortality by 20-40% depending on age and screening frequency 2.
  • The code Z12.31 applies regardless of breast density, though supplemental screening may be considered for dense breasts 1.
  • Screening should continue as long as life expectancy exceeds 10 years, as mortality benefits require approximately 11 years to fully manifest 2.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Breast Cancer Screening Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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