From the Guidelines
Persistent allergic rhinitis and sinus-related coughing should be managed with a daily non-sedating antihistamine and a nasal corticosteroid spray, as these treatments have been shown to be effective in reducing symptoms and improving quality of life. The symptoms of persistent allergic rhinitis and sinus-related coughing include nasal congestion, runny nose, post-nasal drip, sneezing, itchy or watery eyes, sinus pressure, and a chronic cough that worsens at night or when lying down 1. For relief, start with a daily non-sedating antihistamine like cetirizine (10mg) or loratadine (10mg), combined with a nasal corticosteroid spray such as fluticasone (1-2 sprays per nostril daily) or mometasone. Saline nasal rinses using a neti pot or squeeze bottle can help clear mucus and allergens.
Some key points to consider when managing persistent allergic rhinitis and sinus-related coughing include:
- Identifying and avoiding specific allergen triggers is essential for long-term management 1
- Keeping your living space clean and using air purifiers with HEPA filters can help reduce exposure to allergens 1
- For breakthrough symptoms, consider adding a decongestant like pseudoephedrine (avoid with high blood pressure) for short-term use only (3-5 days maximum) 1
- If symptoms don't improve within 2-3 weeks of consistent treatment, consult a healthcare provider as you may need prescription medications or further evaluation 1
It's also important to note that antibiotics should be reserved for acute rhinosinusitis with persistent symptoms for more than 10 days, onset of severe symptoms or signs of high fever (>39 °C) and purulent nasal discharge or facial pain lasting for at least 3 consecutive days, or onset of worsening symptoms following a typical viral illness that lasted 5 days that was initially improving 1.
Overall, the goal of treatment is to reduce symptoms, improve quality of life, and prevent complications. By following these guidelines and working with a healthcare provider, individuals with persistent allergic rhinitis and sinus-related coughing can effectively manage their symptoms and improve their overall health.
From the FDA Drug Label
The FDA drug label does not answer the question.
From the Research
Symptoms of Persistent Allergy Rhythm and Sinusist Coughing
- The symptoms of persistent allergy rhythm and sinusist coughing can be alleviated with various treatments, including montelukast, antihistamines, and combination therapies 2, 3, 4, 5, 6.
- Montelukast alone or in combination with antihistamines has been shown to significantly improve nasal symptoms in patients with persistent allergic rhinitis 2, 5, 6.
- The combination of loratadine and montelukast has been found to be effective in reducing total nasal symptom scores and improving quality of life in patients with allergic rhinitis 4, 5.
- Montelukast has been shown to be more effective than placebo in improving daytime and nighttime nasal symptom scores, as well as rhinoconjunctivitis quality-of-life questionnaires 6.
- Combination therapy with montelukast and an oral antihistamine has been found to be superior to either montelukast or an oral antihistamine alone in improving symptoms of allergic rhinitis 5, 6.
Treatment Options
- Montelukast alone or in combination with antihistamines, such as loratadine or desloratadine, can be used to treat persistent allergic rhinitis 2, 3, 4, 5, 6.
- Intranasal corticosteroids, such as fluticasone, can also be used to treat allergic rhinitis, and have been shown to be effective in reducing nasal symptoms 3, 6.
- Combination therapy with montelukast and an oral antihistamine can be used to treat patients with moderate to severe allergic rhinitis, or those who do not respond to monotherapy 5, 6.
Efficacy and Safety
- Montelukast has been shown to be safe and effective in treating allergic rhinitis, with a low incidence of adverse events 2, 4, 6.
- The combination of loratadine and montelukast has been found to be well-tolerated, with a similar incidence of adverse events to placebo 4.
- Montelukast has been shown to be more effective than placebo in improving symptoms of allergic rhinitis, and combination therapy with an oral antihistamine can provide additional benefits 5, 6.