Is Zicam (zinc) safe to use during pregnancy?

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Last updated: January 13, 2026View editorial policy

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Zicam (Zinc) Safety in Pregnancy

Zinc supplements, including Zicam, are safe to use during pregnancy with strong evidence supporting their use for pregnant patients seeking cold remedies or natural therapies.

Safety Profile and Recommendations

The American Academy of Dermatology provides a "strong" recommendation for zinc supplementation in pregnancy based on moderate quality evidence, representing the highest level of recommendation strength available in the medical literature for zinc use during pregnancy. 1

Key Safety Points

  • Zinc supplements can be used without concern for maternal or fetal safety according to North American clinical practice guidelines 1
  • The recommendation strength is classified as "strong" rather than "conditional," indicating high confidence in the safety profile 1
  • The quality of evidence is rated as "moderate," which is substantially better than the "very low" quality evidence available for most over-the-counter medications evaluated during pregnancy 1

Clinical Application

  • For pregnant patients seeking natural therapies or cold remedies, zinc supplements represent a safe option with documented safety evidence specifically evaluated for pregnancy use 1
  • Standard prenatal zinc supplementation ranges of 15-25 mg daily are well-established as safe 1
  • Unlike many over-the-counter medications that lack robust pregnancy data, zinc has documented safety evidence specifically evaluated for pregnancy use 1

Important Context

While approximately 90% of pregnant women use medications during pregnancy, and 10% of birth defects are directly linked to medications taken during pregnancy, zinc stands out as having strong safety evidence 2. The general principle that no drug is entirely without side-effects and great caution should be taken when prescribing in pregnancy still applies 3, but zinc's documented safety profile makes it a preferred option for pregnant women seeking cold symptom relief.

References

Guideline

Zinc Supplementation in Pregnancy

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Research

Safety of Over-the-Counter Medications in Pregnancy.

MCN. The American journal of maternal child nursing, 2019

Research

Drugs in pregnancy. Drugs to avoid.

Best practice & research. Clinical obstetrics & gynaecology, 2001

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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