Can gout occur in the shoulder?

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Last updated: April 13, 2025View editorial policy

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From the Guidelines

Yes, gout can occur in the shoulder, as it can develop in any joint of the body, including large joints like the shoulder, as noted in the 2012 American College of Rheumatology guidelines for management of gout 1. While gout most commonly affects the big toe joint, it can also affect other joints, including the shoulder. Gout is caused by elevated uric acid levels in the blood (hyperuricemia), which leads to the formation of urate crystals that deposit in joints, causing inflammation, severe pain, redness, and swelling.

  • The 2012 American College of Rheumatology guidelines for management of gout 1 consider the shoulder as one of the large joints that can be involved in gouty arthritis, along with other joints like the ankle, knee, wrist, elbow, and hip.
  • Shoulder gout may present as sudden, intense pain, limited range of motion, warmth, and tenderness in the shoulder joint.
  • If you suspect shoulder gout, seek medical evaluation for proper diagnosis, which typically involves joint fluid analysis to identify urate crystals.
  • Treatment usually includes NSAIDs or colchicine for acute attacks, along with rest and ice application.
  • For long-term management, medications that lower uric acid levels may be prescribed, along with lifestyle modifications including weight management, limiting alcohol intake, avoiding purine-rich foods, and staying hydrated to help prevent future gout attacks in any joint, including the shoulder.

From the Research

Gout in the Shoulder

  • Gout is a common form of acute inflammatory arthritis caused by the deposition of monosodium urate crystals within the synovium of joints 2, 3, 4, 5, 6.
  • While the studies do not specifically mention the shoulder as a common site for gout, they do mention that gout can affect peripheral joints and bursae 4.
  • The deposition of monosodium urate crystals can lead to severe pain, swelling, and tenderness in the affected joint or bursa, which could potentially occur in the shoulder 2, 3, 4, 5, 6.
  • Diagnosis of gout can be made using several validated clinical prediction rules, and arthrocentesis should be performed when suspicion for an underlying septic joint is present 4.
  • Treatment for gout includes colchicine, nonsteroidal anti-inflammatory drugs, and corticosteroids for acute flares, as well as urate-lowering therapies such as allopurinol and febuxostat to prevent future flares 2, 3, 4, 5, 6.

Symptoms and Treatment

  • Symptoms of gout in the shoulder may include severe pain, swelling, and tenderness in the shoulder joint or surrounding bursae 4.
  • Treatment for gout in the shoulder would likely involve a combination of anti-inflammatory medications and urate-lowering therapies, as well as lifestyle modifications to reduce the risk of future flares 2, 3, 4, 5, 6.
  • Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used to treat acute gout, and may be effective in reducing pain and inflammation in the shoulder 6.
  • However, it is essential to note that the studies do not provide direct evidence for the treatment of gout in the shoulder, and further research would be needed to confirm the effectiveness of these treatments for this specific condition.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

An update on the pharmacotherapy of gout.

Expert opinion on pharmacotherapy, 2025

Research

What's new on the front-line of gout pharmacotherapy?

Expert opinion on pharmacotherapy, 2022

Research

Gout: Rapid Evidence Review.

American family physician, 2020

Research

Advances in pharmacotherapy for the treatment of gout.

Expert opinion on pharmacotherapy, 2015

Research

Non-steroidal anti-inflammatory drugs for acute gout.

The Cochrane database of systematic reviews, 2021

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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