From the Guidelines
If Enstilar foam feels too greasy on your scalp, consider switching to a solution-based calcipotriol/betamethasone product like Dovobet solution or Xamiol gel, which are specifically formulated for scalp application with less greasy texture. According to the most recent guidelines, treatment with calcipotriene foam for 8 weeks and calcipotriene plus betamethasone dipropionate gel for 4 to 12 weeks compared with placebo was safe and effective for the treatment of mild to moderate scalp psoriasis 1. Other options include:
- Separate calcipotriol and corticosteroid solutions, such as Dovonex solution and a betamethasone valerate solution, applied separately
- Coal tar shampoos (like T/Gel or Polytar) for severe cases
- Salicylic acid preparations to help remove scales
- Prescription options like calcineurin inhibitors (tacrolimus or pimecrolimus) for severe cases
- Steroid-only solutions like clobetasol propionate (Dermovate) or betamethasone valerate (Betnovate) for short-term use. The choice of vehicle can significantly alter the use and penetration of the medication, and different vehicles are indicated for different body sites, including hair-bearing areas like the scalp 1. Always consult your healthcare provider before switching medications to ensure the alternative is appropriate for your specific condition and to get proper usage instructions.
From the Research
Alternatives to Enstilar Foam
If Enstilar foam is too greasy on the scalp, there are alternative formulations available.
- Calcipotriene and betamethasone dipropionate come in ointment, gel/suspension, and foam formulations 2.
- A foam formulation for the fixed-dose combination of calcipotriol and betamethasone dipropionate (Cal/BD) is available for the treatment of psoriasis vulgaris 3.
- Calcipotriene and Betamethasone Dipropionate PAD-Cream is another option, which may be less greasy and more convenient than foam or gel formulations 4.
- Fixed-dose Cal/BDP is available in different formulations, including ointment, gel, foam, and cream, providing various options for patients 5.
Characteristics of Alternative Formulations
- The PAD-Cream formulation has shown greater treatment efficacy in patients with moderate-to-severe psoriasis compared to topical suspension/gel 4.
- The combination therapy of calcipotriol and betamethasone dipropionate has a rapid onset of action and a simplified dosing regimen, which can improve long-term adherence and patient outcomes 5.
- The dual-action of Cal/BDP targets the inflammatory pathways and abnormal keratinocyte proliferation, providing a therapeutic effect for psoriasis treatment 5.