From the FDA Drug Label
Active Ingredient Hydrocortisone 1% The FDA drug label does not answer the question.
From the Research
For mild allergic reactions causing dry, puffy eyelids, a low-potency hydrocortisone cream 0.5% or 1% can be applied very sparingly to the affected skin around the eyes twice daily for up to 5-7 days. Apply a thin layer using a clean fingertip, being extremely careful to avoid getting the medication in the eyes. This should be used as a short-term solution only, as prolonged use of steroids around the eyes can potentially cause glaucoma, cataracts, or skin thinning. The hydrocortisone works by reducing inflammation and suppressing the immune response that causes the allergic reaction. While using the cream, continue the oral loratadine as prescribed 1, 2. If symptoms don't improve within a few days, or if they worsen, discontinue the hydrocortisone and consult a healthcare provider. For persistent eyelid dermatitis, a medical evaluation may be needed to rule out other conditions or to consider prescription alternatives specifically formulated for use around the eyes. Some studies have shown that loratadine is effective in treating allergic reactions 3, 4, but the provided evidence does not specifically address the use of topical hydrocortisone cream for dry, puffy eyelids. However, a more recent study comparing the antiallergic effects of second-generation H1-antihistamines found that ebastine was more effective than cetirizine or loratadine in alleviating symptoms of seasonal allergic rhinitis 5. Despite this, the use of topical hydrocortisone cream remains a common and effective treatment for mild allergic reactions, and its use should be continued with caution and under medical supervision.