What are the guidelines for using a combination of fenofibrate and a statin, such as atorvastatin (atorvastatin) or rosuvastatin (rosuvastatin), in an adult patient with high triglyceride levels, low high-density lipoprotein (HDL) cholesterol, and a history of cardiovascular disease or multiple risk factors for cardiovascular events, with consideration for potential risks and benefits, and monitoring for impaired renal function, liver enzyme elevations, and muscle toxicity?

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Last updated: January 14, 2026 • View editorial policy

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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