What is the cause of a scalp mass?

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Last updated: April 13, 2025View editorial policy

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Differential Diagnosis for a Lump on the Scalp

  • Single Most Likely Diagnosis
    • Seborrheic keratosis: A common, benign skin growth that can appear on the scalp, often due to aging and sun exposure. It's usually harmless but can be removed for cosmetic reasons.
  • Other Likely Diagnoses
    • Cyst (epidermoid or pilar): Benign cysts that can form on the scalp due to blocked oil glands or hair follicles. They can become inflamed or infected.
    • Lipoma: A benign tumor composed of fat tissue, which can occur on the scalp. It's usually soft and movable.
    • Dermatofibroma: A small, hard bump that can develop on the scalp after a minor injury, likely resulting from the clustering of immune cells and fibroblasts.
  • Do Not Miss Diagnoses
    • Squamous cell carcinoma: A type of skin cancer that can appear on the scalp, especially in areas exposed to the sun. Early detection is crucial for effective treatment.
    • Basal cell carcinoma: The most common form of skin cancer, which can also occur on the scalp. It's usually slow-growing but can be destructive if left untreated.
    • Metastatic tumor: Although rare, a lump on the scalp could be a metastasis from another cancer, such as breast, lung, or melanoma. This would be particularly concerning in patients with a known history of cancer.
  • Rare Diagnoses
    • Pilomatrixoma: A rare, benign tumor that originates from the hair follicle matrix. It's more common in children and young adults.
    • Trichoepithelioma: A rare, benign tumor of hair follicle origin, which can appear on the scalp. It may be solitary or multiple.
    • Angiolipoma: A rare, benign tumor composed of blood vessels and fat tissue. It can occur on the scalp and may be painful due to its vascular nature.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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