From the Research
Yes, Lexapro (escitalopram) can potentially cause breast enlargement in some individuals, as it is a selective serotonin reuptake inhibitor (SSRI) that can influence hormone levels, particularly by increasing prolactin levels in some patients. This side effect, known as gynecomastia in men or breast enlargement in women, is relatively uncommon but has been reported in clinical practice 1. The breast enlargement may develop gradually after starting the medication and can affect one or both breasts.
Causes and Mechanisms
The exact mechanism of SSRI-induced breast enlargement is not fully understood, but it is thought to be related to the increase in prolactin levels, which stimulates breast tissue growth and milk production 2. Other factors, such as changes in hormone levels and individual susceptibility, may also play a role.
Diagnosis and Management
If you experience breast enlargement while taking Lexapro, you should discuss this with your healthcare provider rather than discontinuing the medication on your own. Your doctor might consider adjusting your dosage, switching to a different antidepressant, or ordering tests to rule out other potential causes of breast changes 3. The effect is typically reversible once the medication is stopped or changed, though it may take time for breast size to return to normal.
Key Considerations
It is essential to note that breast enlargement can be a symptom of an underlying condition, and a thorough medical evaluation is necessary to rule out other potential causes 4. Additionally, the use of selective estrogen receptor modulators (SERMs), aromatase inhibitors (AIs), or non-aromatizable androgens is not recommended for the treatment of gynecomastia in general, as their effectiveness and safety have not been established 3.
Recommendations
If you are taking Lexapro and experience breast enlargement, you should consult your healthcare provider to discuss the best course of action, which may include adjusting your medication regimen or undergoing further evaluation to rule out other potential causes. It is crucial to prioritize your health and well-being, and your healthcare provider can help you make informed decisions about your treatment.