Is Albuterol Light Sensitive?
Yes, albuterol is light sensitive and must be protected from light during storage. 1
Storage Requirements
The FDA-approved drug label explicitly states that albuterol sulfate inhalation solution must be stored with specific light protection measures 1:
- "Protect from light" is a mandatory storage instruction 1
- Store between 2°C and 25°C (36°F and 77°F) 1
- Discard if solution becomes discolored 1
- The solution should remain clear, colorless to light yellow 1
Clinical Implications for Storage
Light exposure can degrade albuterol, leading to discoloration and loss of potency. 1 This is particularly important for:
- Nebulizer solutions stored in unit-dose vials, which should be kept in their protective foil pouches until use 1
- Pharmacy dispensing, where the original light-protective packaging should be maintained 1
- Home storage, where patients should avoid leaving albuterol solutions on windowsills or in direct sunlight 1
Visual Inspection Before Use
Healthcare providers and patients should inspect albuterol solution before each use 1:
- Normal appearance: clear, colorless to light yellow 1
- Discard immediately if discolored, as this indicates degradation from light exposure or other factors 1
Practical Considerations
While the metered-dose inhaler (MDI) formulations have some inherent protection from their opaque canisters, nebulizer solutions in clear plastic vials are particularly vulnerable to photodegradation 1. The light sensitivity requirement applies across all formulations but is most critical for liquid preparations 1.