For a patient presenting with knee pain and numbness over the tuberosity area after a fall on the knees, should the initial magnetic resonance imaging (MRI) be performed with or without contrast?

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MRI Without Contrast for Post-Fall Knee Pain

For a patient with knee pain and numbness over the tuberosity area after a fall, order MRI of the knee WITHOUT intravenous contrast after obtaining initial radiographs. 1, 2

Imaging Algorithm

Step 1: Initial Radiographs First

  • Always obtain knee radiographs as the first imaging study in acute knee trauma, regardless of clinical presentation 1
  • Radiographs are essential to exclude fractures before proceeding to advanced imaging 2
  • This is the standard of care per the American College of Radiology guidelines 1

Step 2: MRI Without Contrast as Next Study

  • After radiographs show no fracture, MRI knee WITHOUT IV contrast is the appropriate next imaging study 1, 2
  • The American College of Radiology explicitly recommends MRI without contrast for evaluation of suspected occult fractures or internal derangement after falls 1
  • This applies to both adults and children (skeletally mature and immature) 1

Why MRI Without Contrast is Sufficient

What Non-Contrast MRI Detects

  • Bone marrow contusions and occult fractures that are invisible on radiographs but cause significant morbidity 1, 2, 3
  • Meniscal tears and ligamentous injuries (ACL, PCL, collateral ligaments) 1, 3
  • Patellar tendinopathy and quadriceps tendon injury, particularly relevant given pain over the tuberosity area 2, 3
  • Osteochondritis dissecans in adolescents 2
  • Articular cartilage abnormalities and joint effusion extent 2

When Contrast IS Needed (Not Your Case)

  • MRA (MR arthrography) is reserved for suspected vascular injuries in the setting of knee dislocation or significant trauma with suspected popliteal artery injury 1, 4
  • Vascular injury occurs in approximately 30% of posterior knee dislocations and requires prompt surgical intervention 1
  • Your patient's presentation (fall with tuberosity pain/numbness) does not suggest vascular injury or dislocation 1

Critical Pitfalls to Avoid

Do Not Skip MRI If Symptoms Persist

  • Never assume normal radiographs exclude significant injury 2, 3
  • Meniscal tears, ligament injuries, and bone marrow contusions are invisible on radiographs but cause substantial morbidity 2, 3
  • The American College of Radiology explicitly warns against skipping MRI when symptoms persist after negative radiographs 2, 3

Consider Specific Pathology at Tuberosity

  • Numbness over the tuberosity area suggests nerve involvement (infrapatellar branch of saphenous nerve) or bone marrow edema 2
  • Patellar tendon pathology or tibial tubercle injury should be high on the differential given the anatomic location 2, 3
  • In adolescents, consider Osgood-Schlatter disease (traction apophysitis), though this typically presents with chronic rather than acute post-fall pain 5

Do Not Order Contrast Unnecessarily

  • Standard MRI without contrast has superb soft tissue resolution for all internal derangement evaluation 1
  • Contrast adds cost, time, and potential adverse reactions without improving diagnostic accuracy for your clinical scenario 1
  • Reserve MRA for cases with suspected or confirmed knee dislocation requiring vascular assessment 1, 4

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Knee Injury Evaluation After a Fall

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Guideline

Differential Diagnosis for Inferior Knee Pain After Fall with Normal X-Ray

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Guideline

Management of Knee Injuries After Falls

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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