What is the mortality rate for quadruple coronary artery bypass grafting (CABG) during the operation itself?

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Last updated: April 13, 2025View editorial policy

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From the Guidelines

The mortality rate for quadruple bypass surgery is approximately 1-4% for the operation itself, with the overall operative mortality for CABG being between these percentages, depending on the population studied. This means that about 96-99% of patients survive the immediate surgical procedure. The risk varies significantly based on individual factors such as age, overall health status, presence of other medical conditions like diabetes or kidney disease, left ventricular function, and whether the surgery is performed as an emergency or elective procedure [ 1 ]. Older patients and those with significant comorbidities face higher risks. Some key points to consider include:

  • The use of extra-corporeal circulation (cardiopulmonary bypass) to perform coronary artery surgery remains the most commonly used approach [ 1 ].
  • So-called ‘off-pump’ surgery may lead to a reduction in perioperative mortality and morbidity, but its use should be applied cautiously and selectively to patients with good target vessels and significant co-morbidity [ 1 ].
  • The surgical mortality has improved substantially over recent decades due to advances in surgical techniques, anesthesia management, and perioperative care. Some of the key factors that influence the mortality rate for quadruple bypass surgery include:
  • Age and overall health status of the patient
  • Presence of other medical conditions like diabetes or kidney disease
  • Left ventricular function
  • Whether the surgery is performed as an emergency or elective procedure
  • The experience and skill of the surgical team It's essential to note that while the immediate surgical risk is relatively low, the recovery period carries additional risks that extend beyond the operation itself, and individual risks and benefits should be discussed thoroughly with patients [ 1 ].

From the Research

Mortality Rate for Quadruple Bypass

  • The mortality rate for the operation itself for quadruple bypass is reported to be 3% in a study published in 1976 2.
  • This study analyzed 30 patients who underwent quadruple coronary artery bypass grafting and found that one patient died after the operation.
  • Another study published in 1981 reported an operative mortality rate of 3.7% for coronary bypass surgery, but it did not specifically focus on quadruple bypass 3.
  • More recent studies have compared the outcomes of coronary artery bypass grafting (CABG) with percutaneous coronary intervention (PCI), but they do not provide specific mortality rates for quadruple bypass 4, 5, 6.
  • It is essential to note that the mortality rate for quadruple bypass may vary depending on the patient's overall health, the complexity of the procedure, and the surgeon's experience.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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