What Diabetic Patients Can Do to Diminish Foot Neuropathy
The single most important action is achieving near-normal blood glucose control (HbA1c 6-7%), which can significantly delay neuropathy development in type 1 diabetes and modestly slow progression in type 2 diabetes, though it will not reverse existing nerve damage. 1
Glycemic Control: The Foundation
- Maintain blood glucose levels as close to normal as safely possible, as this is the only intervention proven to prevent or slow diabetic peripheral neuropathy progression 1
- Target HbA1c of 6-7% for most patients, though this should be adjusted in elderly patients or those with significant comorbidities to avoid hypoglycemia 2
- Monitor fasting glucose daily and check 2-hour postprandial glucose 3-4 times weekly after the largest meal 2
- Understand that while tight glycemic control prevents further nerve damage, it does not restore sensation already lost 1
Modifiable Risk Factor Management
Beyond glucose control, address these critical risk factors:
- Stop smoking immediately, as smoking significantly increases vascular disease complications that worsen neuropathy 1
- Control blood pressure, as hypertension is an independent risk factor for neuropathy development and progression 1, 2
- Manage lipid levels (cholesterol and triglycerides), which can aid in preventing neuropathy progression in type 2 diabetes 1
- Achieve weight loss if overweight, as lifestyle intervention focused on dietary weight loss improves neuropathy symptoms 2
- Screen for and correct vitamin B12 deficiency, particularly if taking metformin, as deficiency worsens neuropathy 2, 3
Daily Foot Care and Surveillance
Patients must perform daily foot inspections since up to 50% of neuropathy is asymptomatic but still increases ulceration and amputation risk: 1
- Visually inspect both feet every single day for cuts, blisters, redness, swelling, calluses, or any skin breakdown 1
- Use hand palpation to feel for warmth or areas of increased pressure if visual inspection is difficult 1
- Check between all toes for moisture, cracking, or fungal infections 1
- If unable to see or reach feet due to visual difficulties or physical constraints, have a family member perform daily inspections 1
Proper Footwear Selection and Use
- Wear well-fitted walking shoes or athletic shoes that cushion and redistribute pressure on the feet 1
- Break in new shoes gradually over several days to minimize blister and ulcer formation 1
- Consider extra-wide or depth shoes if bony deformities like hammertoes, prominent metatarsal heads, or bunions are present 1
- Never walk barefoot, even indoors, due to loss of protective sensation 1
- Inspect the inside of shoes daily for foreign objects, torn linings, or rough areas before wearing 1
Skin and Nail Care
- Treat dry skin immediately with moisturizing lotions (but not between toes) to prevent cracking that can lead to infection 1
- Address minor skin conditions like athlete's foot (tinea pedis) promptly to prevent progression to more serious infections 1
- Have calluses debrided by a foot care specialist or trained health professional rather than attempting self-removal 1
- Trim toenails straight across and file sharp edges, or have a podiatrist perform nail care if vision or mobility is impaired 1
Physical Activity and Exercise
- Engage in regular aerobic exercise and physical activity, which can improve neuropathy symptoms through multiple mechanisms 2
- Exercise also helps with weight management and glycemic control, providing dual benefits 2
Professional Medical Care
- See a healthcare provider for foot examination at every visit if neuropathy is present 1
- Undergo annual 10-g monofilament testing to identify feet at risk for ulceration and amputation 1
- Seek immediate medical attention for any foot wound, no matter how minor, as healing is impaired and infection risk is high 1
- Consider referral to a podiatrist for specialized foot care, particularly if high-risk conditions exist 2
Common Pitfalls to Avoid
- Do not use heating pads or hot water bottles on feet, as loss of temperature sensation can result in burns 1
- Avoid self-treatment of corns, calluses, or ingrown toenails with sharp instruments or chemical agents 1
- Do not ignore minor foot problems, as they can rapidly progress to serious complications in the presence of neuropathy 1
- Do not assume pain relief means the neuropathy is improving—symptomatic treatment does not reverse nerve damage 1
Understanding Limitations
While these measures are critical for preventing complications, currently no treatment can reverse underlying nerve damage once it has occurred 1. The focus must be on prevention through glycemic control and meticulous foot care to avoid ulceration, infection, and amputation. Patients should understand that even with optimal management, existing numbness or loss of sensation will not improve, making preventive strategies absolutely essential 1.