Treatment of Bell's Palsy
Prescribe oral corticosteroids within 72 hours of symptom onset—this is the only proven effective treatment that significantly improves facial nerve recovery. 1
Immediate First-Line Treatment
Oral corticosteroids must be initiated within 72 hours of symptom onset for patients 16 years and older. 1 The evidence is compelling: 83% recovery at 3 months with prednisolone versus 63.6% with placebo, and 94.4% recovery at 9 months versus 81.6% with placebo. 1
Recommended Corticosteroid Regimens
Choose one of these evidence-based regimens:
- Prednisolone 50 mg daily for 10 days 1
- Prednisone 60 mg daily for 5 days, followed by a 5-day taper 1
For patients significantly below or above average weight, consider weight-based dosing of 1 mg/kg/day (maximum 60 mg/day). 1
Critical Timing Consideration
Do not initiate corticosteroids beyond 72 hours of symptom onset—there is no evidence of benefit after this window. 1 Delaying treatment beyond 72 hours reduces effectiveness. 1
Antiviral Therapy: Limited Role
Never prescribe antiviral therapy alone—it is completely ineffective as monotherapy. 1, 2
You may offer combination therapy (oral antiviral plus corticosteroids) within 72 hours, but understand the added benefit is minimal. 1 Some evidence shows 96.5% complete recovery with combination therapy versus 89.7% with steroids alone, but this small benefit must be weighed against minimal risks. 1
If choosing combination therapy:
- Valacyclovir 1 g three times daily for 7 days 2, OR
- Acyclovir 400 mg five times daily for 10 days 1, 2
Eye Protection: Mandatory and Critical
Implement aggressive eye protection immediately for all patients with impaired eye closure to prevent permanent corneal damage. 1
Structured Eye Protection Protocol
Daytime protection:
- Lubricating ophthalmic drops every 1-2 hours while awake 1
- Sunglasses outdoors to protect against wind and foreign particles 1
Nighttime protection:
- Ophthalmic ointment at bedtime for sustained moisture retention 1
- Eye taping or patching with careful instruction on proper technique to avoid corneal abrasion 1
- Consider moisture chambers using polyethylene covers for severe cases 1
Urgent ophthalmology referral required for:
- Severe impairment with complete inability to close the eye 1
- Eye pain, vision changes, redness, discharge, or foreign body sensation 1
- Any signs of corneal exposure or damage 1
Common Eye Protection Pitfall
Improper eye taping technique can cause corneal abrasion—patients must receive careful instruction. 1 Relying solely on drops without nighttime protection can lead to exposure keratitis. 1
Treatments NOT Recommended
Do not order routine laboratory testing or diagnostic imaging for typical Bell's palsy presentations. 1 These tests do not aid diagnosis and delay treatment. 1
Do not prescribe physical therapy—there is no proven benefit over spontaneous recovery. 1
Do not recommend acupuncture—poor quality evidence shows an indeterminate benefit-harm ratio. 1
Do not perform surgical decompression except in rare specialized cases. 1
Special Populations
Children
Children have better prognosis with higher spontaneous recovery rates (up to 90%). 2 The benefit of corticosteroid treatment in children is inconclusive. 1 Consider oral corticosteroids on an individualized basis with substantial caregiver participation in shared decision-making, particularly for severe or complete paralysis. 1 Use prednisolone 1 mg/kg/day (maximum 50-60 mg) for 5 days followed by a 5-day taper if treatment is chosen. 1
Pregnant Women
Treat pregnant women with oral corticosteroids within 72 hours using the same regimens as non-pregnant adults, with careful individualized assessment of benefits and risks. 1 Eye protection measures are essential and safe in pregnancy. 1
Mandatory Follow-Up and Referral Triggers
Reassess or refer to a facial nerve specialist at 3 months if facial recovery is incomplete. 1
Immediate reassessment or referral required at any time for:
- New or worsening neurologic findings (suggests stroke, tumor, or CNS pathology) 1, 3
- Development of ocular symptoms 1
- Progressive weakness beyond 3 weeks (red flag for alternative diagnosis) 3
Early follow-up at 1-2 weeks is valuable for monitoring recovery progress, reinforcing eye protection, and identifying complications. 1
Atypical Features Requiring Imaging
Order MRI with and without contrast if any of these features are present:
- Recurrent paralysis on the same side 3
- Bilateral facial weakness 3
- Isolated branch paralysis 3
- Other cranial nerve involvement 3
- No recovery after 3 months 1
- Progressive weakness beyond 3 weeks 3
These features suggest tumor, stroke, Lyme disease, sarcoidosis, or other alternative diagnoses requiring different management. 3
Prognosis and Natural History
Approximately 70% of patients with complete paralysis recover completely within 6 months, while those with incomplete paralysis have recovery rates up to 94%. 1, 2 Most patients begin showing recovery within 2-3 weeks, with complete recovery typically occurring within 3-4 months. 1
However, 30% may experience permanent facial weakness with muscle contractures, requiring long-term management including potential reconstructive surgery, ophthalmology follow-up for persistent lagophthalmos, and psychological support for quality of life issues. 1