What is the diagnosis for a 30-year-old woman, gravida (number of times pregnant) 2, para (number of viable births) 1, at 28 weeks gestation, presenting with severe abdominal pain, nausea, hypertension, and tachycardia, with a history of tobacco use, polysubstance drug use, and peptic ulcer disease?

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Differential Diagnosis for Abdominal Pain in a 30-year-old Pregnant Woman

  • Single most likely diagnosis:
    • Placental abruption: The patient's severe abdominal pain, hypertension, and uterine tenderness are consistent with placental abruption, a condition where the placenta separates from the uterus. The history of tobacco use and lack of prenatal care increase her risk for this condition.
  • Other Likely diagnoses:
    • Preterm labor: The patient's contractions every 1-2 minutes and abdominal pain could indicate preterm labor, especially given her history of a previous cesarean delivery.
    • Uterine rupture: Although less likely, the patient's history of a previous cesarean delivery and severe abdominal pain raise the possibility of uterine rupture, which is a life-threatening emergency.
    • Peptic ulcer disease exacerbation: The patient's history of peptic ulcer disease and current abdominal pain could suggest an exacerbation of her condition, although the location and radiation of pain are atypical.
  • Do Not Miss diagnoses:
    • Eclampsia: Although the patient does not have a headache or vision changes, her hypertension and abdominal pain necessitate consideration of eclampsia, a condition that can rapidly progress to seizures and is life-threatening.
    • Uterine dehiscence: Similar to uterine rupture, dehiscence (a partial tear) can occur, especially in a patient with a previous cesarean delivery, and requires prompt diagnosis and management.
    • Ovarian torsion: Although less common during pregnancy, ovarian torsion can cause severe abdominal pain and requires immediate surgical intervention to preserve the ovary.
  • Rare diagnoses:
    • Hepatic rupture: A rare but life-threatening condition that can cause severe abdominal pain and is associated with pregnancy, particularly in the setting of preeclampsia or trauma.
    • Acute fatty liver of pregnancy: A rare condition characterized by abdominal pain, nausea, and liver dysfunction, which can rapidly progress to liver failure if not recognized and managed promptly.

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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