From the Research
Bupropion Dosage for Appetite Suppression
The starting dose of Bupropion (Wellbutrin) for appetite suppression is not explicitly stated in the provided studies as a primary indication. However, based on the studies related to weight loss, the following information can be gathered:
- The study 1 used a dose of 300 mg/d for 8 weeks in overweight and obese women with binge-eating disorder.
- The study 2 started with a dose of 300 mg/d and increased to 400 mg/d if weight loss was less than 5% at week 12.
- The study 3 started with a dose of 100 mg/d and gradually increased to a maximum of 200 mg twice daily.
Key Findings
- Bupropion was found to be effective in facilitating weight loss in obese adults with depressive symptoms 2.
- Bupropion was more effective than placebo in achieving weight loss at 8 weeks in overweight and obese adult women 3.
- The most common side effect of bupropion is dry mouth, and it is generally well-tolerated 4, 5.
Dosage Considerations
- The dosage of bupropion for weight loss or appetite suppression may vary depending on the individual and the specific formulation used (IR, SR, or XR) 5.
- It is essential to follow the recommended dosage and administration schedule to minimize the risk of side effects and ensure optimal efficacy.