From the Research
Chronic Inflammatory Response Syndrome (CIRS) from black mold exposure requires immediate removal from the contaminated environment and a comprehensive treatment approach, prioritizing the Shoemaker Protocol as the most effective treatment, as documented in the literature review by 1. The treatment protocol typically involves a step-wise approach, starting with binding agents like cholestyramine or Welchol to help remove mold toxins from the body. These binders should be taken away from food and other medications.
- Key considerations in the treatment of CIRS include:
- Addressing inflammation with medications like VIP nasal spray or low-dose naltrexone
- Antifungal treatments, such as fluconazole or itraconazole, to target fungal infections
- Supporting detoxification pathways with glutathione, N-acetylcysteine, and methylation support to help the body clear toxins
- The role of vitamin C in immune function, as discussed in 2, highlights its potential benefits in supporting immune defense and reducing oxidative stress, although its direct application in CIRS treatment is not explicitly stated.
- It is essential to prioritize the most recent and highest-quality evidence, such as the 2024 literature review by 1, which emphasizes the effectiveness of the Shoemaker Protocol in treating CIRS, over older studies or those with less direct relevance to the condition.
- The treatment of CIRS should focus on eliminating exposure, addressing inflammatory and immune dysregulation, and supporting the body's natural detoxification processes, as outlined in the comprehensive approach guided by the Shoemaker Protocol, as supported by 1.