What causes pain on the palmar aspect of the wrist and with wrist flexion?

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Last updated: February 14, 2025View editorial policy

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Differential Diagnosis for Anterior Wrist Pain and Pain with Wrist Flexing

  • Single Most Likely Diagnosis
    • Ganglion cyst: This is a common cause of anterior wrist pain, especially when it occurs on the volar aspect of the wrist. Pain with wrist flexing can be exacerbated by the cyst's presence.
  • Other Likely Diagnoses
    • Carpal tunnel syndrome: Although it typically presents with numbness and tingling, carpal tunnel syndrome can also cause anterior wrist pain, especially with flexion.
    • Wrist tendinitis (e.g., flexor carpi radialis or flexor carpi ulnaris): Inflammation of the tendons on the volar aspect of the wrist can cause pain with wrist flexion.
    • Triangular fibrocartilage complex (TFCC) injury: Although more commonly associated with ulnar-sided wrist pain, TFCC injuries can sometimes cause anterior wrist pain, especially with rotational movements.
  • Do Not Miss Diagnoses
    • Infection (e.g., septic arthritis or osteomyelitis): Although less common, infections in the wrist can cause severe pain, swelling, and limited mobility. Early diagnosis and treatment are crucial to prevent long-term damage.
    • Fracture (e.g., scaphoid or distal radius): Fractures can cause anterior wrist pain, especially with movement. Missing a fracture can lead to complications like nonunion or malunion.
  • Rare Diagnoses
    • Kienböck's disease (avascular necrosis of the lunate): A rare condition that can cause anterior wrist pain, especially with flexion.
    • Giant cell tumor of the tendon sheath: A rare, benign tumor that can cause anterior wrist pain and swelling.
    • Rheumatoid arthritis: Although not typically presenting with isolated anterior wrist pain, rheumatoid arthritis can cause wrist pain and stiffness, including with flexion.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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