What is the appropriate management for an elderly patient on Xarelto (rivaroxaban) who has experienced a ground level fall?

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Sample HPI for Ground-Level Fall on Xarelto

For an elderly patient on Xarelto (rivaroxaban) presenting after a ground-level fall, document a comprehensive trauma-focused history that prioritizes detection of occult injuries and bleeding risk, as these patients face up to 7% mortality and require heightened suspicion for intracranial hemorrhage even without classic signs. 1

Essential Historical Elements to Document

Mechanism and Timing:

  • Exact circumstances of the fall (location, witnessed vs. unwitnessed, any prodrome) 1
  • Time spent on floor/ground before discovery 1
  • Any loss of consciousness or altered mental status during or after fall 1
  • Presence of syncope, near-syncope, or orthostatic symptoms preceding fall 1

Anticoagulation Details:

  • Last dose of Xarelto taken (timing critical - rivaroxaban has rapid onset) 2
  • Current dosing regimen (10 mg, 15 mg, or 20 mg daily) 2
  • Indication for anticoagulation (atrial fibrillation, VTE prophylaxis, etc.) 2
  • Duration of therapy and adherence 1
  • Renal function status if known (CrCl affects rivaroxaban levels significantly) 2

Injury Assessment:

  • Any head strike or direct trauma to head/neck 1
  • Complaints of headache, neck pain, or neurological symptoms 1
  • Presence of visible injuries, bruising, or deformities 1
  • Any bleeding (external or suspected internal - melena, hematemesis) 1

Fall Risk Factors:

  • Number of prior falls in past year 1
  • Gait or balance difficulties 1
  • Visual impairments or peripheral neuropathies 1
  • Footwear at time of fall 1

Comorbidities:

  • Specific high-risk conditions: dementia, Parkinson's disease, prior stroke, diabetes, depression 1
  • Cardiac history including atrial fibrillation/flutter (calculate CHA2DS2-VASc score if applicable) 3
  • Renal impairment (critical for rivaroxaban metabolism) 2

Medication Review:

  • Complete medication list with attention to polypharmacy 1
  • Other antiplatelet agents (aspirin, clopidogrel) - combination increases bleeding risk 4, 5
  • High-risk medications: vasodilators, diuretics, antipsychotics, sedative/hypnotics 1
  • P-glycoprotein or CYP3A4 inhibitors that affect rivaroxaban levels 2
  • Alcohol use 1

Functional Status:

  • Baseline activities of daily living 1
  • Living situation and safety of home environment 1

Critical Clinical Context

Ground-level falls in elderly patients on Xarelto warrant aggressive evaluation because:

  • 6% will sustain fractures, 10-30% may have polytrauma despite seemingly minor mechanism 1
  • Traumatic intracranial hemorrhage occurs in 1.7-4.3% of anticoagulated patients with ground-level falls 4, 5
  • Injuries may be "occult" without classic signs - high-risk injuries include blunt head trauma, spinal fractures, hip fractures 1
  • Mortality in this population reaches 7% even with ground-level falls 1

Key pitfall to avoid: Research shows antiplatelet therapy (aspirin) may confer equal or higher risk of traumatic intracranial hemorrhage compared to anticoagulation in ground-level falls, contrary to traditional teaching 4, 5. Document all antiplatelet agents, not just anticoagulants.

Documentation should answer: "If this patient was a healthy 20-year-old, would they have fallen?" If no, the fall represents a sentinel event requiring comprehensive evaluation beyond trauma assessment 1

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Risk of Intracranial Hemorrhage in Ground-level Fall With Antiplatelet or Anticoagulant Agents.

Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2017

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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