What is the normal standard dispensed size for Metered-Dose Inhaler (MDI) albuterol?

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Last updated: January 15, 2026View editorial policy

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Standard Dispensed Size for Albuterol MDI

The standard albuterol metered-dose inhaler (MDI) is dispensed containing 200 actuations, with each actuation delivering 90 mcg of albuterol. 1

Standard Canister Specifications

  • Each actuation of a standard albuterol MDI contains 90 mcg of albuterol per puff. 1

  • The typical dispensed canister contains 200 metered actuations (8.5 g canister), which represents the most common size prescribed in clinical practice. 2

  • Some manufacturers also produce a smaller 60-actuation canister (6.7 g), though this is less commonly dispensed as a standard size. 2

Dose Counter Integration

  • Modern albuterol HFA MDIs include integrated dose counters that reliably track the number of actuations remaining, with a discrepancy rate of only 1.87 per 200 actuations in clinical use. 2

  • The dose counter provides the only reliable means for patients to track medication remaining, as MDIs contain excess propellant beyond the labeled number of actuations, which may deliver subtherapeutic doses after the labeled count is exceeded. 2

  • Approximately 95-97% of patients report high satisfaction with the integrated dose counter for knowing when the inhaler should be replaced. 2

Clinical Context for Dispensing

  • For acute asthma exacerbations, the recommended dose is 4-8 puffs (360-720 mcg) every 20 minutes for 3 doses, then every 1-4 hours as needed, meaning a 200-actuation canister provides adequate supply for both acute and maintenance therapy. 1

  • A standard 200-actuation canister, when used at typical maintenance dosing of 2 puffs four times daily, provides approximately 25 days of therapy. 1

Important Prescribing Consideration

  • Always prescribe albuterol MDI with a valved holding chamber (spacer), as this delivery method is as effective as nebulized therapy for mild-to-moderate exacerbations when proper technique is used. 1, 3

References

Guideline

Asthma Exacerbation Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Research

Automatic replacement of albuterol nebulizer therapy by metered-dose inhaler and valved holding chamber.

American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2005

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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