Is the contrast used in a Hepatobiliary Iminodiacetic Acid (HIDA) scan safer than regular Intravenous (IV) contrast?

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Last updated: February 14, 2025 • View editorial policy

From the Research

Contrast Safety in HIDA Scans

  • The provided studies do not directly compare the safety of contrast used in Hepatobiliary Iminodiacetic Acid (HIDA) scans to regular Intravenous (IV) contrast 1, 2, 3, 4, 5.
  • HIDA scans use technetium-99m labeled iminodiacetic acid derivatives, which are designed to visualize the hepatobiliary system 1, 2, 3, 4.
  • The studies focus on the diagnostic value and applications of HIDA scans in various clinical settings, such as posttransplantation biliary complications 3, cholecystitis 4, and biliary dyskinesia 5.
  • There is no direct evidence in the provided studies to suggest that the contrast used in HIDA scans is safer than regular IV contrast 1, 2, 3, 4, 5.

Diagnostic Applications of HIDA Scans

  • HIDA scans are used to evaluate the functional integrity of the hepatobiliary system 1.
  • They can help diagnose intrahepatic cholestasis, biliary obstruction, and other hepatobiliary disorders 2.
  • HIDA scans are also used to detect posttransplantation biliary complications, such as biliary leaks and obstruction 3.
  • The scans can provide valuable information on the status of the cystic duct and help diagnose cholecystitis 4.

Limitations and Controversies

  • The predictive value of HIDA scans for laparoscopic cholecystectomy candidacy is debated 5.
  • Negative HIDA scan results can potentially mislead decisions to perform a laparoscopic cholecystectomy 5.

References

Research

Laparoscopic cholecystectomy for ultrasound normal gallbladders: Should we forego hepatobiliary iminodiacetic acid scans?

Canadian journal of rural medicine : the official journal of the Society of Rural Physicians of Canada = Journal canadien de la medecine rurale : le journal officiel de la Societe de medecine rurale du Canada, 2019

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