What is Parsonage-Turner syndrome?

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Last updated: April 14, 2025View editorial policy

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From the Research

Parsonage-Turner syndrome is a rare neurological disorder characterized by sudden, severe pain in the shoulder and upper arm, followed by weakness and muscle wasting, and its treatment primarily focuses on pain management and physical therapy, with high-dose pulsed steroids assisting initial pain control, as suggested by the most recent study 1.

Key Characteristics of Parsonage-Turner Syndrome

  • Sudden, severe pain in the shoulder and upper arm
  • Followed by weakness and muscle wasting
  • Affects the brachial plexus, a network of nerves that controls movement and sensation in the shoulder, arm, and hand
  • Exact cause often unknown, but may be triggered by infections, vaccinations, surgery, or trauma

Treatment and Management

  • Pain management with medications like NSAIDs, gabapentin, or pregabalin during the acute phase
  • Physical therapy to maintain range of motion and strengthen affected muscles during recovery
  • High-dose pulsed steroids may assist initial pain control, as suggested by the most recent study 1
  • Rehabilitation focusing on restoring functional scapular mechanics, energy conservation, contracture prevention, and pain management are critical

Prognosis and Outcomes

  • Most patients eventually recover, though complete recovery can take months to years
  • Some may have residual weakness
  • Early diagnosis and treatment can help improve outcomes and prevent complications like frozen shoulder
  • Lifetime residual pain and weakness are rare, with most making dramatic functional recovery, as noted in the study 1

References

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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