What ICD-10 code is used for a patient with a history of cannabis use disorder who has experienced a recurrence of uncomplicated cannabis dependence?

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Last updated: January 19, 2026View editorial policy

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ICD-10 Coding for Recurrent Cannabis Use

For a patient with a history of cannabis use disorder who has experienced a recurrence of uncomplicated cannabis dependence, use ICD-10 code F12.20 (Cannabis dependence, uncomplicated).

Understanding the Clinical Context

The term "recurrence" in substance use disorders refers to a return to problematic use patterns after a period of remission or abstinence. In the ICD-10-CM coding system, the diagnosis is based on the current clinical presentation rather than the temporal pattern of the disorder 1.

Key Diagnostic Considerations

Cannabis dependence requires meeting criteria for a maladaptive pattern of substance use with clinically significant impairment, manifested by three or more of the following within a 12-month period 1:

  • Tolerance (needing increased amounts or diminished effect)
  • Withdrawal symptoms
  • Using larger amounts or over longer periods than intended
  • Persistent desire or unsuccessful efforts to cut down
  • Significant time spent obtaining, using, or recovering from cannabis
  • Reduced social, occupational, or recreational activities
  • Continued use despite knowledge of persistent problems

Specific ICD-10 Code Selection

F12.20 is the appropriate code when the patient meets dependence criteria without complications such as intoxication, withdrawal, or cannabis-induced psychotic/mood disorders 1.

Alternative Codes to Consider

If the clinical presentation includes specific features, use these codes instead:

  • F12.21: Cannabis dependence, in remission (if currently abstinent and not meeting active criteria)
  • F12.22: Cannabis dependence with intoxication (if presenting with acute intoxication)
  • F12.23: Cannabis dependence with withdrawal (if experiencing withdrawal symptoms within 3 days of cessation) 2, 3
  • F12.24: Cannabis dependence with cannabis-induced mood disorder
  • F12.25: Cannabis dependence with cannabis-induced psychotic disorder 4

Critical Clinical Pitfalls

Do not confuse "recurrence" with "in remission" status. If the patient is actively using cannabis and meeting dependence criteria again, they are no longer in remission and should be coded as F12.20 (current dependence) 1.

Avoid coding cannabis abuse (F12.1x) if dependence criteria are met. By definition, if a patient meets criteria for substance dependence, the diagnosis supersedes abuse 1.

Document withdrawal symptoms carefully. Approximately 10% of chronic cannabis users develop cannabis use disorder, and withdrawal symptoms (irritability, anxiety, sleep disturbances, decreased appetite) typically occur within 3 days of cessation and last up to 14 days 2, 3. If withdrawal is present during the encounter, use F12.23 instead of F12.20.

Prognostic Factors Affecting Recurrence

Research demonstrates that complete abstinence from cannabis after the first episode prevents relapse of psychiatric illness, while all patients who relapsed to cannabis use experienced recurrence of illness 4. Document these risk factors that predict poor prognosis and higher recurrence risk:

  • Early onset of cannabis use (≤18 years)
  • Younger age at onset of first episode
  • Positive family history of psychiatric illness
  • Being unmarried
  • Lower socioeconomic status 4

Early abstinence is critical—abstaining later in the course of illness does not improve outcomes significantly 4.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Health Consequences of Marijuana Use

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Guideline

Cannabis Withdrawal Symptoms

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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