What is the cause of severe left foot pain in an 87-year-old patient with a history of similar episodes, presenting with impaired renal function (GFR of 30), and unable to walk?

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Differential Diagnosis for 87-year-old with Left Foot Pain

Single most likely diagnosis

  • Gout: Given the patient's severe pain, inability to walk, and history of similar episodes, gout is a strong consideration. The patient's reduced GFR (30) also increases the risk of gout due to decreased uric acid excretion.

Other Likely diagnoses

  • Osteoarthritis: The patient's age and severe foot pain could be indicative of osteoarthritis, especially if she has a history of similar pain episodes.
  • Peripheral Artery Disease (PAD): Although less likely given the acute onset, PAD could cause severe leg pain, especially in an elderly patient with potential vascular risk factors.
  • Musculoskeletal strain or sprain: Given the patient's age and potential for decreased mobility, a musculoskeletal injury could be a possible cause of her pain.

Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)

  • Deep Vein Thrombosis (DVT): Although the patient does not have fevers, DVT is a critical diagnosis to consider due to its potential for severe consequences, such as pulmonary embolism.
  • Cellulitis or abscess: Infection is a concern, especially in an elderly patient with decreased mobility and potential compromised skin integrity.
  • Fracture: A stress or insufficiency fracture could cause severe pain and is a critical diagnosis to consider, especially if the patient has osteoporosis or has experienced a recent fall.

Rare diagnoses

  • Pseudogout (Calcium Pyrophosphate Deposition Disease): Although less common than gout, pseudogout could cause similar symptoms, especially in an elderly patient with joint disease.
  • Erythromelalgia: A rare condition characterized by burning pain, heat, and redness in the feet, which could be considered if other diagnoses are ruled out.
  • Complex Regional Pain Syndrome (CRPS): A rare condition characterized by severe, burning pain, usually after an injury or trauma, which could be a possible diagnosis if other causes are excluded.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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