What is the nerve supply of the external anal sphincter?

Nerve Supply of the External Anal Sphincter

The external anal sphincter is primarily innervated by the inferior rectal branches of the pudendal nerve (S2-S4), with additional direct supply from the S4 sacral nerve root in approximately 31% of individuals. 1, 2, 3

Primary Innervation Pattern

The pudendal nerve provides the main motor innervation to the external anal sphincter through three distinct nerve branches 3:

• Anterior ramus: Arises from the external perineal nerve and consistently emerges from the pudendal plexus 3
• Inferior rectal nerve: The primary branch, also consistently arising from the pudendal plexus 3
• Posterior branch: Present in only 31% of cases, originating either directly from S4 or from the inferior rectal nerve 3

Anatomical Distribution and Clinical Relevance

The nerve branches insert into the external anal sphincter with predictable probability patterns 2:

• Peak insertion zone: Between 55-65% of sphincter length (measured from coccyx apex to perineal body), with 0.68 probability of finding nerve branches 2
• High probability zone: 30-85% of sphincter length maintains >0.3 probability of nerve branch presence 2
• Optimal surgical landmark: The most probable nerve location is at the midpoint of sphincter length, corresponding to the 3 o'clock or 9 o'clock position in lithotomy 2

Fiber Composition

The nerve branches contain 2,137-2,896 total nerve fibers with specific composition 3:

• 80% myelinated fibers of varying caliber (motor function) 3
• 20% unmyelinated fibers (autonomic/sensory function) 3

Critical Surgical Considerations

Surgeons must exercise extreme caution when debriding the lower sacral segments (below S3/S4) in patients with pelvic osteomyelitis, as the S2-S4 nerve roots innervating the anal sphincter can be damaged, resulting in permanent fecal incontinence in non-paraplegic patients. 1

The inferior rectal branches of the pelvic plexus run along the conjoint longitudinal muscle coat and enter the anal canal from the superior aspect of the levator ani on the anterolateral side 4. These nerves are vulnerable during:

• Intersphincteric dissections for low rectal cancer 1
• Fistula surgery involving the intersphincteric space 1
• Aggressive sacral debridement procedures 1

Distinction from Internal Sphincter Innervation

The internal anal sphincter receives predominantly sympathetic autonomic innervation from the inferior rectal branches of the pelvic plexus, which differs fundamentally from the somatic motor supply to the external sphincter. 4

• Internal sphincter nerves are primarily sympathetic (>50%) with parasympathetic components 4
• External sphincter receives somatic motor innervation via pudendal nerve 2, 3
• Injury to the inferior rectal branches during surgery causes loss of internal sphincter tone but does not directly affect external sphincter voluntary contraction 4

Common Pitfall to Avoid

Never perform manual anal dilatation, as it causes permanent pudendal nerve stretch injury and incontinence in 10-30% of patients. 5 The pudendal nerve's fixed anatomical course makes it vulnerable to traction injury during forceful sphincter stretching procedures.