What are the symptoms of hypomagnesemia-related neuropathy?

From the Research

Symptoms of Hypomagnesemia-Related Neuropathy

The symptoms of hypomagnesemia-related neuropathy can be varied and include:

• Movement disorders such as postural tremor, resting tremor, intention tremor, ataxia, dysarthria, athetosis, myoclonus, and chorea 1
• Neurologic symptoms like downbeat nystagmus, tetany, drowsiness, vertigo, and proximal muscle weakness 1
• Cerebellar syndromes, which may be a distinct disease entity, characterized by cerebellar edema and corresponding clinical, MRI, and laboratory findings 2
• Peripheral neuropathy, which can be a major dose-limiting factor in patients receiving cis-platinum treatment 3
• Other symptoms like seizures, which can be potentially life-threatening if left untreated 2

Associated Findings

These symptoms can be accompanied by:

• Low serum magnesium levels, often 1.3 mg/dL or lower 1
• Imaging findings such as bilateral cerebellar and vermis hyperintensities 1
• Residual deficits, which can occur in some patients even after treatment 1
• Underlying conditions like diabetes, which can increase the risk of neuropathy 4