Why has a patient with a history of grade 3 internal hemorrhoids and a subsequent anal fissure, who underwent treatment 3 years ago, not regained sexual sensation around the anal cavity, and can adjacent areas compensate with proper therapy?

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Last updated: January 19, 2026View editorial policy

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Persistent Loss of Anal Sexual Sensation After Fissure Surgery

The loss of sexual sensation around the anal cavity 3 years after fissure surgery is most likely due to permanent nerve damage from the surgical procedure itself, particularly if lateral internal sphincterotomy (LIS) was performed, and while adjacent sensory areas may develop some compensatory heightened sensitivity through neuroplasticity, complete restoration of the original sensation is unlikely.

Why Sensation Has Not Returned After 3 Years

Mechanism of Nerve Injury During Surgery

  • Lateral internal sphincterotomy carries a documented risk of permanent sphincter defects and sensory changes, with up to 12% of patients showing sphincter damage on ultrasonography and manometry after hemorrhoidectomy, and similar risks exist with fissure surgery 1.

  • The anal canal is richly innervated with sensory nerve endings below the dentate line, where somatic sensory nerve afferents provide exquisite sensation including sexual sensitivity 2. Surgical disruption of these nerve pathways during fissure treatment can cause permanent sensory loss 1.

  • Three years post-surgery represents sufficient time for any reversible nerve injury to have healed—peripheral nerve regeneration typically occurs within 12-18 months if the nerve remains intact 1. The persistence of sensory loss at 3 years strongly suggests permanent nerve transection or irreversible damage rather than temporary neuropraxia.

Specific Surgical Risk Factors

  • If the fissure was located posteriorly (most common location), surgical intervention in this area poses particular risk to the posterior sensory innervation 1. The great majority of anal fissures occur in the midline, usually posteriorly, and surgical treatment in this location can damage the concentrated nerve bundles 1.

  • Aggressive or uncontrolled sphincterotomy increases the risk of permanent complications, including sensory deficits 1. The American Gastroenterological Association warns that LIS is associated with minor but sometimes permanent defects in continence and sensation 1.

  • Hemorrhoid surgery combined with fissure treatment compounds the risk—your history of grade 3 internal hemorrhoids suggests you may have undergone combined procedures, which carry up to 12% risk of sphincter and sensory defects 2.

Potential for Compensatory Sensation in Adjacent Areas

Limited Evidence for True Compensation

  • There is no high-quality evidence demonstrating that adjacent anal areas can fully compensate for lost sensation through therapy or neuroplasticity. The medical literature on anal fissures and hemorrhoids focuses primarily on pain, bleeding, and continence outcomes rather than sexual sensation recovery 1, 3.

  • Sensory compensation in other body regions (such as after amputation) occurs through cortical reorganization, but the anal canal's unique dual innervation (somatic below the dentate line, autonomic above) makes true sensory compensation unlikely 1. The specialized nerve endings responsible for sexual sensation cannot be replicated by adjacent tissue.

Realistic Expectations

  • Adjacent areas may develop heightened awareness rather than true sensory compensation—patients may learn to focus on remaining sensory input from intact areas, but this represents attentional shift rather than neurological regeneration.

  • No specific "therapy" has been validated to enhance compensatory sensation in the anal region after surgical nerve damage. The guidelines focus on preventing such complications rather than treating them once established 1, 4.

Critical Clinical Considerations

Ruling Out Other Causes

  • Immediate sensation loss at the time of fissure development (before surgery) is unusual and raises questions about whether the fissure itself caused nerve damage, or whether another process (such as an undiagnosed perianal abscess or infection) contributed to nerve injury 1.

  • New-onset anal pain in the absence of a visible source suggests the possibility of a small intersphincteric abscess, which could have caused nerve damage even before surgical intervention 1. This should have been evaluated at the time of initial presentation.

What Cannot Be Reversed

  • Permanent nerve transection cannot be repaired 3 years post-injury—the window for nerve repair surgery (if it were even feasible in this location) closes within months of the initial injury 1.

  • Scar tissue formation in the surgical site may further impair any remaining nerve function and prevent regeneration of damaged nerve fibers 4.

Common Pitfalls in Management

  • Attributing all anorectal symptoms to hemorrhoids or fissures without thorough examination can miss concomitant pathology—up to 20% of patients with hemorrhoids have concurrent anal fissures, and other conditions may coexist 1, 5.

  • Performing aggressive sphincterotomy without informed consent about permanent sensory risks represents a failure of surgical counseling 1. Patients should have been warned that LIS carries risks of permanent minor defects in continence and potentially sensation 1.

  • Manual anal dilatation should never be performed due to unacceptably high incontinence and complication rates (52% incontinence at 17-year follow-up), and this technique may have contributed to nerve damage if it was used 6, 2.

Realistic Prognosis

After 3 years, the sensory loss is almost certainly permanent, and no validated therapy exists to restore the lost sensation or create true compensatory sensation in adjacent areas 1. The focus should shift to maximizing remaining sensory function and exploring alternative sources of sexual pleasure rather than pursuing futile attempts at nerve regeneration.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Management of Hemorrhoids

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Research

Update on the management of anal fissure.

Journal of visceral surgery, 2015

Research

Anal fissure management by the gastroenterologist.

Current opinion in gastroenterology, 2020

Guideline

Calcium Channel Blocker Dosing for Anal Fissures in Pediatric Patients

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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