Does montelukast (Singulair) cure sinusitis-related coughing?

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Last updated: April 14, 2025View editorial policy

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From the Research

Montelukast tablets do not cure sinusitis-related coughing. Montelukast (brand name Singulair) is a leukotriene receptor antagonist primarily used to treat asthma and allergic rhinitis by reducing inflammation in the airways. While it may help reduce symptoms in some patients with sinusitis who have an allergic component to their condition, it is not considered a cure for sinusitis or the coughing associated with it. According to a systematic review and meta-analysis published in 2020 1, montelukast is effective in treating allergic rhinitis, but its effectiveness in treating sinusitis is not well established.

Key Points to Consider

  • Sinusitis cough typically requires treatment directed at the underlying cause, which may include:
    • Antibiotics if bacterial infection is present
    • Nasal corticosteroids
    • Saline irrigation
    • Decongestants
    • Antihistamines depending on the specific cause
  • Montelukast is typically taken as a once-daily tablet (usually 10mg for adults), but should only be used as prescribed by a healthcare provider
  • A study published in 2006 2 found that montelukast is effective in treating asthma and allergic rhinitis, but it does not provide evidence for its use in treating sinusitis
  • Another study published in 2004 3 reviewed the use of montelukast in treating asthma and allergic rhinitis, but did not discuss its use in treating sinusitis
  • A review of acute sinusitis published in 2008 4 discussed various treatment options, including antibiotics, antihistamines, and nasal corticosteroids, but did not mention montelukast as a treatment option

Recommendation

If you're experiencing coughing related to sinusitis, it's best to consult with a healthcare provider for proper diagnosis and a treatment plan tailored to your specific condition, as montelukast alone is unlikely to resolve the problem. A healthcare provider can help determine the underlying cause of the sinusitis and recommend the most effective treatment options.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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