From the Research
For recurrent canker sores, the most effective treatment is a barrier forming hyaluronic acid containing mouth rinse or topical gel formulation, as it has been shown to significantly reduce lesion size, pain, and improve quality of life 1. The use of antiviral medications such as acyclovir or valacyclovir may be helpful if the canker sores are related to herpes simplex virus, but true canker sores (aphthous ulcers) are typically not viral in origin. Some key points to consider when treating recurrent canker sores include:
- Topical treatments like benzocaine gel (Orajel) or hydrogen peroxide rinses may be effective in reducing pain and promoting healing
- Prescription options like dexamethasone oral rinse or triamcinolone dental paste may also be effective
- Preventive measures such as avoiding trigger foods, using SLS-free toothpaste, and maintaining good oral hygiene are also important
- If you experience frequent recurrences (more than 3-4 episodes per year), or if your sores are severe, last longer than two weeks, or are accompanied by fever, consider consulting with a healthcare provider for proper diagnosis and treatment. It's worth noting that amlexanox 5% paste has also been shown to be effective in reducing ulcer size, pain duration, and healing time 2, but the most recent and highest quality study suggests that hyaluronic acid-based products are a valuable alternative to drug-based approaches in the treatment of recurrent aphthous stomatitis (RAS) 1.