Is Veltassa (patiromer) cheaper than Lokelma (sodium zirconium cyclosilicate)?

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Last updated: April 15, 2025View editorial policy

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From the Research

I cannot definitively state whether Valtessa is cheaper than Lokelma as medication prices vary significantly based on location, insurance coverage, pharmacy pricing, and available discounts. Both Valtessa (sodium zirconium cyclosilicate) and Lokelma (sodium zirconium cyclosilicate) are actually the same medication used to treat hyperkalemia (high potassium levels in the blood), just marketed under different brand names in different regions. Valtessa is primarily available in certain European markets while Lokelma is the brand name used in the US and other countries. To determine which is more affordable for your specific situation, you should check with your local pharmacies, insurance provider, or use medication price comparison tools online. Some patients may qualify for patient assistance programs or copay cards that could significantly reduce out-of-pocket costs for either medication. The actual cost to you will depend on your specific healthcare system and coverage, as noted in various studies on hyperkalemia treatment, including those on patiromer and sodium zirconium cyclosilicate 1.

Key Points to Consider

  • Medication prices vary by location and insurance coverage
  • Valtessa and Lokelma are the same medication with different brand names
  • Patient assistance programs or copay cards may reduce out-of-pocket costs
  • Local pharmacies and insurance providers can provide more specific cost information
  • Studies such as 2 and 3 discuss the efficacy and safety of sodium zirconium cyclosilicate in treating hyperkalemia, but do not directly compare prices of Valtessa and Lokelma.

Additional Considerations

  • The choice between Valtessa and Lokelma should be based on individual patient needs and circumstances, rather than just cost
  • Healthcare providers should consider factors such as patient health status, other medications being taken, and potential side effects when deciding which medication to prescribe
  • As noted in 4, patiromer and sodium zirconium cyclosilicate have improved upon the standard treatment for hyperkalemia, but the cost of these medications can vary.
  • The most recent study 1 provides a systematic review and meta-analysis of patiromer and sodium zirconium cyclosilicate, but does not address the cost comparison between Valtessa and Lokelma.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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