Severe Fingertip Pain: Differential Diagnosis and Management
Severe pain localized to the fingertip most commonly indicates infection (felon or paronychia), acute trauma with occult fracture, or glomus tumor, and requires urgent evaluation to prevent tissue loss and permanent disability. 1
Immediate Red Flags Requiring Urgent Evaluation
- Infection: Felon (pulp space infection) or paronychia present with throbbing pain, swelling, erythema, and warmth—these are true emergencies requiring antibiotics and often surgical drainage to prevent osteomyelitis and tissue necrosis 1
- Vascular compromise: Ischemic fingertip pain represents a true emergency where tissue viability depends on prompt intervention within hours 1
- Acute trauma: Even without obvious deformity, severe fingertip pain after injury may indicate tuft fracture, nail bed injury, or subungual hematoma requiring drainage 2
Systematic Approach to Diagnosis
Clinical History Priorities
- Trauma history: Recent injury suggests fracture, nail bed laceration, or soft tissue damage requiring specific management 2
- Infection symptoms: Fever, progressive swelling, purulent drainage, or systemic symptoms mandate immediate treatment 1
- Chronic intermittent pain: Exquisite focal tenderness with cold sensitivity suggests glomus tumor, a benign but intensely painful vascular lesion typically under the nail 1
- Occupational factors: Repetitive trauma or vibrating tool use increases risk of various fingertip pathologies 3
Physical Examination Essentials
- Vascular assessment: Check capillary refill, color, and temperature—any compromise requires immediate vascular surgery consultation 1
- Infection signs: Fluctuance, purulence, or tracking erythema up the finger indicates need for surgical drainage 1
- Sensory testing: Numbness suggests nerve injury or compression requiring specialized evaluation 1
- Nail examination: Subungual hematoma >50% of nail bed area requires trephination for pain relief 2
Diagnostic Imaging Strategy
Initial Radiographs
- Always obtain plain radiographs first for fingertip pain to exclude fracture, foreign body, osteomyelitis, or bone tumor 4
- Standard views include PA, lateral, and oblique projections of the affected digit 4
Advanced Imaging When Radiographs Are Normal
- MRI without contrast is the preferred study for suspected occult fracture, glomus tumor, or soft tissue pathology when radiographs are nondiagnostic 4
- Ultrasound is appropriate for evaluating soft tissue masses, foreign bodies, or tendon pathology at the fingertip 4
- MRI demonstrates bone marrow edema from occult fractures and can identify small glomus tumors that cause disproportionate pain 4
Common Specific Diagnoses
Felon (Pulp Space Infection)
- Presents with severe throbbing pain, tense swelling of the fingertip pulp, and inability to tolerate touch 1
- Requires urgent surgical drainage and IV antibiotics to prevent osteomyelitis and fingertip necrosis 1
- Referral to hand surgeon is mandatory 1
Paronychia
- Infection along the nail fold with erythema, swelling, and purulent drainage 1
- Early cases may respond to warm soaks and oral antibiotics, but established abscesses require incision and drainage 1
Glomus Tumor
- Benign vascular tumor causing severe focal pain, cold sensitivity, and point tenderness (often under nail) 1
- MRI is diagnostic and surgical excision is curative 1
Tuft Fracture
- Distal phalanx fracture from crush injury causing severe pain and subungual hematoma 2
- Treatment focuses on nail bed repair if lacerated and pain control; most heal with conservative management 2
Critical Management Principles
Infection and ischemia are the two conditions that cannot wait—both require intervention within hours to prevent permanent tissue loss and disability 1
When to Refer to Hand Surgery
- Any suspected deep space infection (felon, septic flexor tenosynovitis) 1
- Vascular compromise or ischemic pain 1
- Complex nail bed injuries requiring microsurgical repair 2
- Suspected glomus tumor requiring excision 1
Conservative Management Appropriate For
- Simple paronychia without abscess: warm soaks and oral antibiotics 1
- Minor tuft fractures without nail bed injury: buddy taping and analgesia 2
- Subungual hematoma <50% nail area without fracture: observation or simple trephination 2
Common Pitfalls to Avoid
- Never dismiss severe fingertip pain as minor—the intensity of pain often correlates with serious pathology like infection or glomus tumor 1
- Do not delay drainage of suspected felon—waiting for "pointing" allows infection to spread to bone and cause permanent damage 1
- Always obtain radiographs—occult fractures and foreign bodies are easily missed clinically 2
- Consider glomus tumor in chronic focal fingertip pain—this diagnosis is frequently delayed because the tumor is too small to palpate 1