From the Research
For a vape cartridge containing 700mg THC and 50mg CBG, it is recommended to start with the lowest possible dose, often referred to as "microdosing," which typically involves a single 2-3 second inhalation, and wait at least 15-30 minutes to assess effects before considering additional doses. This approach is based on the understanding that proper dosing varies significantly between individuals due to factors like prior cannabis experience, tolerance, body weight, and the specific medical condition being treated 1, 2, 3, 4, 5. The effects from vaporized cannabis typically onset within minutes and may last 2-4 hours. Given the variability in individual responses to cannabinoids, it is crucial to consult with a healthcare provider who specializes in cannabis medicine to develop a personalized treatment plan for specific needs and to ensure this product is appropriate for the condition being treated. Key considerations include the potential for synergistic or antagonistic effects between different cannabinoids, as noted in studies on binary mixtures of cannabinoids 5, and the importance of selecting an appropriate formulation to enhance bioavailability, as seen with the use of certain solvents like Cremophor EL in improving the dissolution of lipophilic drugs 4. Ultimately, the goal is to minimize unwanted side effects while finding the optimal therapeutic dose, emphasizing the need for personalized medical guidance.