What is the differential diagnosis (DDx) for a 51-year-old male patient with a tender lump near the left pubic tubercle area, normal hernial orifices, and no cough impulse, which is mostly palpable when standing?

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Differential Diagnosis for a 51-year-old Male with a Tender Lump near the Left Pubic Tubercle

  • Single most likely diagnosis:
    • Inguinal ligament strain or enthesopathy: This condition is likely given the location of the pain (towards the left pubic tubercle area) and the fact that it's mostly palpable when standing, suggesting a mechanical or strain-related issue.
  • Other Likely diagnoses:
    • Osteitis pubis: Inflammation of the pubic bone and its surrounding structures, which could cause tenderness in the area, especially if the patient has a history of athletic activity or trauma.
    • Pubic bone stress fracture: A possible cause, especially if the patient has been engaging in repetitive stress activities or has osteoporosis, though less common in men without specific risk factors.
    • Soft tissue tumor (e.g., lipoma, cyst): Although less likely, a soft tissue tumor could present as a palpable lump in this area, especially if it's growing and causing discomfort.
  • Do Not Miss diagnoses:
    • Testicular cancer with metastasis to the pubic area: Although rare, testicular cancer can metastasize to unusual locations, including the pubic bone or surrounding soft tissues, making it crucial not to miss this potentially life-threatening condition.
    • Osteomyelitis of the pubic bone: An infection of the bone that could present with localized pain and swelling, which is critical to diagnose and treat promptly to avoid serious complications.
    • Metastatic disease to the pubic bone: Various cancers can metastasize to the bones, including the pubic bone, and present with pain and a palpable mass, making this a critical diagnosis not to overlook.
  • Rare diagnoses:
    • Bursitis of the iliopectineal bursa: Although bursitis can occur in various locations, inflammation of the iliopectineal bursa is less common and could potentially cause pain and swelling in the area near the pubic tubercle.
    • Avulsion fracture of the pubic bone: Typically associated with significant trauma, an avulsion fracture could present with acute pain and a palpable defect in the bone, though this would be less common in the absence of a reported traumatic event.

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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