What are the symptoms and treatment options for a patient with a kidney stone?

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Last updated: January 21, 2026View editorial policy

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Kidney Stone Symptoms

Kidney stones typically present with severe loin pain (renal colic), accompanied by frequent urination, dysuria, oliguria, and hematuria. 1

Classic Symptom Presentation

The hallmark symptom complex includes:

  • Severe flank/loin pain that can radiate to the groin, caused by ureteral irritation and trauma as stones move through the ureter 2, 1
  • Hematuria (blood in urine), which occurs in the majority of symptomatic cases 1
  • Urinary symptoms including dysuria (painful urination), urinary frequency, and oliguria (reduced urine output) 1
  • Fever may develop, particularly if infection is present 3

Important Clinical Distinctions

Nonobstructing lower pole stones, particularly those <5 mm, are often completely asymptomatic and discovered incidentally. 2 This is a critical point: small, stationary stones rarely cause spontaneous bleeding or symptoms unless they begin to move 2.

Precipitating Factors

Acute renal colic can be triggered by:

  • Dehydration and reduced urine output 1
  • Increased protein intake 1
  • Heavy physical exercise 1
  • Certain medications (protease inhibitors, antibiotics, some diuretics) 4

Common Pitfall to Avoid

Do not attribute hematuria to tiny nonobstructing stones without considering other sources, particularly in older males where prostatic and bladder pathology are common. 2 Mild hematuria after stone manipulation procedures occurs in approximately 50% of cases, but spontaneous bleeding from small, stationary stones is uncommon 2.

When Symptoms Warrant Intervention

Stones smaller than 5 mm normally pass spontaneously within 17 days (range 6-29 days), with passage rates of 75%. 5, 1 Spontaneous passage rates vary by location: 68-83% for distal ureteral stones, 58-70% for mid-ureteral stones, and 49-52% for upper ureteral stones 5.

For stones >5 mm in the distal ureter, medical expulsive therapy (α-blockers) provides the greatest benefit. 5, 3

Emergency Symptoms Requiring Urgent Intervention

In cases of sepsis and/or anuria in an obstructed kidney, urgent decompression via percutaneous nephrostomy or ureteral stenting is mandatory. 5 Warning signs include:

  • Fever with obstructive symptoms suggesting infected obstructed kidney 5
  • Anuria (no urine output) 5
  • Signs of sepsis (high fever, elevated CRP, hemodynamic instability) 5

References

Guideline

Hematuria Evaluation and Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Research

Kidney Disease: Kidney Stones.

FP essentials, 2021

Research

Treatment and prevention of kidney stones: an update.

American family physician, 2011

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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