What causes testicular pain during micturition (urination)?

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Last updated: April 15, 2025 • View editorial policy

Differential Diagnosis for Testicle Pain during Urination

Single Most Likely Diagnosis

  • Urinary Tract Infection (UTI): This is a common condition that can cause pain in the testicles during urination due to the proximity of the testicles to the urinary tract and the potential for referred pain.

Other Likely Diagnoses

  • Epididymitis: Inflammation of the epididymis, often caused by bacterial infection, can lead to testicle pain that may worsen during urination.
  • Prostatitis: Inflammation of the prostate gland can cause pain in the testicles, perineum, or penis, and this pain may be exacerbated during urination.
  • Urethritis: Inflammation of the urethra, often due to infection, can cause dysuria (painful urination) and may be associated with testicle pain.

Do Not Miss Diagnoses

  • Testicular Torsion: Although less common, testicular torsion is a medical emergency that can cause severe testicle pain and may be associated with nausea, vomiting, and abdominal pain. It requires immediate attention to preserve the testicle.
  • Appendicitis: In some cases, appendicitis can present with testicle pain, especially if the appendix is located near the testicles (retrocecal appendix). This is a surgical emergency.
  • Kidney Stone: A kidney stone passing through the urinary tract can cause severe pain, including testicle pain during urination, and requires prompt medical evaluation.

Rare Diagnoses

  • Orchitis: Inflammation of one or both testicles, usually caused by bacterial or viral infection, can lead to testicle pain.
  • Varicocele: Enlargement of the veins within the scrotum can cause aching pain in the testicles, which might be noticed during urination due to increased abdominal pressure.
  • Henoch-Schönlein Purpura (HSP): A rare condition that can cause testicular pain among other symptoms like purpura, arthritis, and abdominal pain.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.