Are there anxiety medications that help with dermatological issues?

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Last updated: April 15, 2025View editorial policy

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From the Guidelines

Yes, there are anxiety medications that can help with certain dermatological issues, particularly those exacerbated by stress and anxiety, as supported by the joint AAD-NPF guidelines of care for the management and treatment of psoriasis with awareness and attention to comorbidities 1. When considering the management of dermatological issues with anxiety medications, it's crucial to prioritize the patient's mental health. The guidelines suggest that psoriasis-specific therapy is recommended as a measure to improve psoriasis-associated anxiety and depression in individuals with psoriasis 1. Some key points to consider when treating dermatological issues with anxiety medications include:

  • Selective serotonin reuptake inhibitors (SSRIs) may be prescribed for conditions like psychogenic excoriation (skin picking) and trichotillomania (hair pulling)
  • Benzodiazepines like lorazepam (Ativan) or clonazepam (Klonopin) can provide short-term relief for acute flare-ups of skin conditions worsened by anxiety, but should be used cautiously due to dependency risks
  • Antihistamines with anxiolytic properties, such as hydroxyzine (Atarax), can be effective for anxiety-related skin conditions that involve itching It's essential to consult with both a dermatologist and psychiatrist or primary care physician to determine the most appropriate medication and dosage for your specific condition, as patients with psoriasis should be referred to an appropriate health care professional for further assessment and management if they show signs or symptoms of anxiety, depression, or suicidal ideation 1.

From the Research

Anxiety Medications and Dermatological Issues

  • There is evidence to suggest that certain anxiety medications, such as selective serotonin reuptake inhibitors (SSRIs), may have a positive effect on dermatological issues 2.
  • A study found that patients with psoriasis who were treated with SSRIs had a decreased need for systemic psoriasis treatment, indicating a potential link between anxiety medications and improved dermatological outcomes 2.
  • Another study discussed the use of various medications, including SSRIs, in emergency dermatological situations, highlighting their potential role in managing dermatological conditions 3.
  • SSRIs have been shown to be effective in treating a range of conditions, including anxiety and depression, and may also have a positive impact on dermatological issues such as chronic pruritus 4, 5.
  • The treatment of chronic pruritus, a condition characterized by intense itching, may involve the use of antidepressants, including SSRIs, to help manage symptoms and improve quality of life 5.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

A Clinical Review of Common Medications Used in Emergency Dermatological Situations.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2019

Research

Selective serotonin-reuptake inhibitors: an update.

Harvard review of psychiatry, 1999

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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