What is the diagnosis of submandibular (below the mandible) swelling?

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Last updated: February 14, 2025View editorial policy

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Differential Diagnosis for Submandibular Swelling

Single Most Likely Diagnosis

  • Submandibular sialadenitis: This is an inflammation of the submandibular gland, often caused by bacterial infection, which can lead to swelling in the submandibular area. It's a common condition that can be acute or chronic and is frequently seen in clinical practice.

Other Likely Diagnoses

  • Submandibular gland stones (sialolithiasis): Stones in the submandibular gland can cause obstruction and subsequent swelling. This condition is relatively common and should be considered in the differential diagnosis.
  • Dental infections: Infections originating from the teeth, especially the lower molars, can spread to the submandibular space and cause swelling.
  • Lymphadenitis: Inflammation of the lymph nodes in the submandibular area can cause swelling and is often due to infection.
  • Submandibular gland tumors: Both benign (like pleomorphic adenomas) and malignant tumors can cause swelling in the submandibular area, though they are less common than inflammatory conditions.

Do Not Miss Diagnoses

  • Ludwig's angina: A severe infection of the submandibular space that can cause significant swelling and is life-threatening if not promptly treated. It's crucial to identify this condition early due to its potential for airway compromise.
  • Submandibular abscess: An abscess in the submandibular space can cause severe swelling and is a medical emergency requiring drainage.
  • Necrotizing fasciitis: A rare but deadly infection of the soft tissues that can cause swelling and requires immediate medical attention.

Rare Diagnoses

  • Sarcoidosis: A systemic disease that can cause swelling in the submandibular gland among other symptoms.
  • Sjögren's syndrome: An autoimmune disorder that can affect the salivary glands, including the submandibular gland, leading to swelling.
  • Kimura disease: A rare, chronic inflammatory disorder that can cause swelling in the submandibular area, often associated with lymphadenopathy and eosinophilia.
  • Branchial cleft cysts: Congenital anomalies that can present as swellings in the submandibular area, typically discovered in childhood but can be diagnosed at any age.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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