PCDC Dosing for Submental Fat Reduction
I cannot provide dosing recommendations for PCDC (phosphatidylcholine/deoxycholate) for submental fat reduction because the evidence provided exclusively addresses antibiotic dosing for infectious diseases, not aesthetic injectable treatments for submental fullness.
Critical Context Mismatch
The question asks about PCDC dosing for the submentum (the area under the chin), which in aesthetic medicine refers to:
- Injectable treatments for submental fat reduction (commonly called "double chin" treatment)
- Deoxycholic acid injections (FDA-approved as Kybella/ATX-101)
- Off-label phosphatidylcholine/deoxycholate compound injections
However, all provided evidence 1, 2 addresses:
- Penicillin dosing for bacterial infections (endocarditis, meningitis, intra-abdominal infections)
- Antibiotic selection for various infectious conditions
- Antimicrobial stewardship principles
What You May Be Looking For
If you meant penicillin for a submental space infection:
- For odontogenic infections involving the submental space, empiric therapy typically includes coverage for oral flora
- Standard regimens would involve beta-lactam/beta-lactamase inhibitor combinations
- Specific dosing would be amoxicillin-clavulanate 875/125 mg twice daily for adults 2
If you meant aesthetic PCDC injections:
- This requires consultation of dermatology/plastic surgery literature
- FDA-approved deoxycholic acid (Kybella) dosing is typically 2 mg/cm² per treatment area
- Off-label PCDC formulations have variable concentrations and no standardized guidelines
Please clarify whether you are asking about infectious disease treatment or aesthetic procedures, as these are entirely different clinical contexts requiring different evidence sources.