What is the significance of a thyroid lobe cyst?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: February 14, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Research

Significance of a Thyroid Lobe Cyst

  • A thyroid lobe cyst can be a significant finding, as it may be associated with malignant tumors, such as papillary carcinoma 1.
  • The presence of a cystic lesion in the thyroid gland can be evaluated using fine-needle aspiration biopsy (FNAB), which can help diagnose benign or malignant conditions 2, 3.
  • In some cases, a thyroid lobe cyst can be an intra-thyroid thyroglossal duct cyst, which is a rare condition that can be diagnosed using FNAB and treated surgically 4, 3.
  • Cystic thyroid lesions in children can be a heterogeneous group of disease states, ranging from benign to malignant tumors, and require careful evaluation and management 5.

Diagnostic Evaluation

  • Fine-needle aspiration biopsy (FNAB) is a useful diagnostic tool for evaluating cystic thyroid lesions, and can help diagnose benign or malignant conditions 2, 3.
  • Ultrasonography can be used to evaluate the characteristics of the cyst, such as its size and location, and can help guide FNAB 4, 5.
  • Radionuclide imaging can be used to evaluate the functional status of the thyroid gland, but may not be as useful in evaluating cystic lesions 5.

Treatment Options

  • Surgical resection is a common treatment option for thyroid lobe cysts, particularly if malignancy is suspected or confirmed 1, 3.
  • A Sistrunk procedure, which includes removal of the median portion of the hyoid bone, may be necessary if a thyroglossal duct tract is present 1, 3.
  • Observation, aspiration, or cyst sclerosis may be considered for benign cystic lesions, but surgical resection may be necessary if the cyst is large or symptomatic 5.

References

Research

Papillary carcinoma of a thyroglossal duct cyst in a patient with thyroid hemiagenesis: effectiveness of conservative surgical treatment.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 2008

Research

Intrathyroid cysts of thyroglossal duct origin.

The American surgeon, 1998

Research

An intra-thyroid thyroglossal duct cyst.

European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie, 2005

Research

Cystic thyroid lesions in children.

Journal of pediatric surgery, 1998

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.